Abstract Advanced receiver structures capable of suppressing multiple-access interference in code-division multiple-access (CDMA) systems operating in frequency-selective fading channels are considered in this thesis. The aim of the thesis is to develop and validate novel receiver concepts suitable for future wideband cellular CDMA systems. Data detection and synchronization both for downlink and uplink receivers are studied. The linear minimum mean squared error (LMMSE) receivers are derived and analyzed in frequency-selective fading channels. Different versions of the LMMSE receivers are shown to be suitable for different data rates. The precombining LMMSE receiver, whichis also suitable for relatively fast fading channels, is shown to improve the performance of the conventional RAKE receivers signicantly in the FRAMES wideband CDMA concept. It is observed that the performance of the conventional RAKE receivers is degraded signicantly with highest data rates due to multiple-access interference (MAI) as well as due to inter-path interference. Based on a general convergence analysis, it is observed that the postcombining LMMSE receivers are mainly suited to the high data rate indoor systems. The blind adaptive LMMSE-RAKE receiverdeveloped for relatively fast fading frequency-selective channels gives superior rate of convergence and bit error rate (BER) performance in comparison to other blind adaptive receivers based on least mean squares algorithms. The minimum variance method based delay estimation in blind adaptive receivers is shown to result in improved delay acquisition performance in comparison to the conventional matched filter and subspace based acquisition schemes. A novel delay tracking algorithm suitable to blind least squares receivers is also proposed. The analysis shows improved tracking performance in comparison to the standard delay-locked loops. Parallel interference cancellation (PIC) receivers are developed for the uplink. Data detection, channel estimation, delay acquisition, delay tracking, inter-cell interference suppression, and array processing in PIC receivers are considered. A multistage data detector with the tentative data decision and the channel estimate feedback from the last stage is developed. Adaptive channel estimation filters are used to improve the channel estimation accuracy. The PIC method is also applied to the timing synchronization of the receiver. It is shown that the PIC based delay acquisition and tracking methods can be used to improve the performance of the conventional synchronization schemes. Although the overall performance of the PIC receiver is relatively good in the single-cell case, its performance is signicantly degraded in a multi-cell environment due to unknown signal components which degrade the MAI estimates and subsequently the cancellation efficiency. The blind receiver concepts developed for the downlink are integrated into the PIC receivers for inter-cell interference suppression. The resulting LMMSE-PIC receiver is capable of suppressing residual interference and results in good BER performance in the presence of unknown signal components.