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1	Variabilität molekularer axialer Differenzierung am Beginn der Gastrulation beim Kaninchen / Variability of molecular axial differentiation at the beginning of gastrulation in the rabbit Plitzner, Juliane 30 April 2008 (has links) No description available. 570 Biowissenschaften, Biologie Mathematics and Computer Science Kaninchen Achsenentwicklung Dkk 1 Cer 1 Lefty Hex rabbit development body axes Dkk 1 Cer 1 Lefty Hex 42.67 Fortpflanzung Entwicklung WKF 300 Embryologie Wachstum
2	Časo-prostorové utváření molekulárních gradientů v časném embryonálním vývoji Xenopus laevis. / Formation of spatio-temporal molecular gradients in early embryonic development of Xenopus laevis. Šídová, Monika January 2015 (has links) Clarifying the underlying spatio-temporal mechanisms that determine body pattern is important for detailed understanding of embryonic development. A crucial question of vertebrate embryogenesis remains: when and how are single blastomeres determined for differentiation that subsequently leads to body axes specification and the formation of different tissues and organs? The answer to this question will be beneficial for primary research as well as in the field of applied medicine. The main aim of the presented thesis was to study spatio-temporal molecular gradients of cell fate determinants during early embryonic development. The African clawed frog Xenopus laevis was used as a model organism because of their large size of oocytes and external embryonic development. Due to late activation of embryonic transcription, a crucial mechanism of early blastomeres determination is dependent on asymmetric localization of maternal factors within oocyte and their uneven distribution into single blastomeres during early cell division. Two main localization patterns were identified along the animal-vegetal axis of the mature Xenopus oocyte using qPCR tomography. The localization gradient with preference in either animal or vegetal hemisphere was found for maternal mRNA as well as miRNAs. Moreover, two vegetal...

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Variabilität molekularer axialer Differenzierung am Beginn der Gastrulation beim Kaninchen / Variability of molecular axial differentiation at the beginning of gastrulation in the rabbit

Časo-prostorové utváření molekulárních gradientů v časném embryonálním vývoji Xenopus laevis. / Formation of spatio-temporal molecular gradients in early embryonic development of Xenopus laevis.