The thesis describes investigations into two contrasting aspects of Slow Wave Sleep (SWS). The first is a laboratory based study of the effects of passive heating on the subsequent SWS of six healthy subjects, and the second employs home sleep recording techniques to investigate the prevalence and characteristics of the 'alpha sleep anomaly' in volunteers from the local community.

Thesis (Ph. D.)--Auburn University. / Abstract. Vita. Includes bibliographical references (p. 148-174).

Heat acclimation increases the local heat loss responses of sweating and skin blood flow which is thought to persist for up to 3 weeks post-acclimation. However, the extent to which increases in local heat loss affect whole-body heat loss as a function of increasing levels of heat stress remains unresolved. Using direct calorimetry, we examined changes in whole-body evaporative heat loss (EHL) during progressive increases in metabolic heat production 1) prior to (Day 0), during (Day 7) and following a 14-day heat acclimation protocol (Day 14) – Induction phase, and; 2) at the end of a 1-week (Day 21) and 2-week decay period (Day 28) – Decay phase. Ten males performed intermittent exercise (3 x 30-min (min) bouts of cycling at 300 (Ex1), 350 (Ex2), and 400 watts•meters2 (W•m2) (Ex3) separated by 10 and 20 min rest periods, respectively). During the induction period, EHL at Day 7 was increased at each of the three exercise bouts (Ex1: + 6%; Ex2 +8%; Ex3: +13%, all p≤0.05) relative to Day 0 (EHL at Ex1: 529 W; Ex2: 625 W; Ex3: 666 W). At Day 14, EHL was increased for all three exercise bouts compared to Day 0 (Ex1: 9%; Ex2: 12%; Ex3: 18%, all p≤0.05). As a result, a lower cumulative change in body heat content (ΔHb) was measured at Day 7 (-30%, p≤0.001) and Day 14 (-47%, p≤0.001). During the decay phase, EHL at Day 21 and 28 was only reduced in Ex 3 (p≤0.05) compared to Day 14. In parallel, ΔHb increased by 39% (p=0.003) and 57% (p≤0.001) on Day 21 and Day 28 relative to Day 14, respectively. When Day 28 was compared to Day 0, EHL remained elevated in each of the exercise bouts (p≤0.05). As such, ΔHb remained significantly lower on Day 28 compared to Day 0 (-16%, p=0.042). We show that 14 days of heat acclimation increases whole-body EHL during exercise in the heat which is maintained 14 days post-acclimation.

Heat acclimation increases the local heat loss responses of sweating and skin blood flow which is thought to persist for up to 3 weeks post-acclimation. However, the extent to which increases in local heat loss affect whole-body heat loss as a function of increasing levels of heat stress remains unresolved. Using direct calorimetry, we examined changes in whole-body evaporative heat loss (EHL) during progressive increases in metabolic heat production 1) prior to (Day 0), during (Day 7) and following a 14-day heat acclimation protocol (Day 14) – Induction phase, and; 2) at the end of a 1-week (Day 21) and 2-week decay period (Day 28) – Decay phase. Ten males performed intermittent exercise (3 x 30-min (min) bouts of cycling at 300 (Ex1), 350 (Ex2), and 400 watts•meters2 (W•m2) (Ex3) separated by 10 and 20 min rest periods, respectively). During the induction period, EHL at Day 7 was increased at each of the three exercise bouts (Ex1: + 6%; Ex2 +8%; Ex3: +13%, all p≤0.05) relative to Day 0 (EHL at Ex1: 529 W; Ex2: 625 W; Ex3: 666 W). At Day 14, EHL was increased for all three exercise bouts compared to Day 0 (Ex1: 9%; Ex2: 12%; Ex3: 18%, all p≤0.05). As a result, a lower cumulative change in body heat content (ΔHb) was measured at Day 7 (-30%, p≤0.001) and Day 14 (-47%, p≤0.001). During the decay phase, EHL at Day 21 and 28 was only reduced in Ex 3 (p≤0.05) compared to Day 14. In parallel, ΔHb increased by 39% (p=0.003) and 57% (p≤0.001) on Day 21 and Day 28 relative to Day 14, respectively. When Day 28 was compared to Day 0, EHL remained elevated in each of the exercise bouts (p≤0.05). As such, ΔHb remained significantly lower on Day 28 compared to Day 0 (-16%, p=0.042). We show that 14 days of heat acclimation increases whole-body EHL during exercise in the heat which is maintained 14 days post-acclimation.

As human dependence on electronic devices grows, there is an emerging need on finding sustainable power sources for low power electronics and sensors. One of the promising possibilities in this space is the human body itself. Harvesting significant power from daily human activities will have a transformative effect on wearables and implantables. One of the main challenges in harvesting mechanical energy from human actions is to ensure that there is no effect on the body itself. For this reason, any intrusive mechanism will not have practical relevance. In this dissertation, novel non-intrusive energy harvesting technologies are investigated that can capture available energy from body, motion, and surroundings. Energy harvesting from the body is explored by developing a wrist-based thermoelectric harvester that can operate at low-temperature gradients. Energy harvesting from motion is investigated by creating a backpack and shoe sole. These devices passively store kinetic energy in a spring that is later released to a generator when it is not intrusive to the user kinematics. Lastly, energy harvesting from immediate surroundings is investigated by designing a two degree of freedom vibration absorber that is excited by electromagnetic fields found in common household appliances. These novel solutions are shown to provide consistent electrical power from wasted energy. Harvester designs are extensively modeled and optimized device architectures are manufactured and tested to quantify the relevant parameters such as output voltage and power density. / Doctor of Philosophy / Energy harvesting is the action to transform energy in the form of heat, relative motion, light, etc. into useful electrical energy. An example of an energy harvester is a solar cell which converts energy in the form of light to electricity. Our body consumes a considerable amount of energy to maintain our body temperature and achieve everyday movements, i.e., walking, jumping, etc. The purpose of this research was to fabricate, model and test wearable energy harvesters in the form of a backpack, a shoe sole, a watch, and a cantilever beam to charge mobile electronics on the go. Electrical energy is harvested from human motion by using the relative displacement between the human torso and a payload. Similarly, the ankle joint is used to produce electricity by using the relative rotation between the foot and shank. The difference in temperature between the ambient air and the human body is used to generate enough electricity to power a wrist watch. Finally, energy is harvested from everyday surroundings by using a cantilever beam which absorbs magnetic fields coming from power cords and able to power sensors.