- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 1 to 10 of 91 (0.067 seconds)| 1 |
Attentional functions of the locus ceruleus noradrenergic systemSelden, Nathan Richard Webb January 1989 (has links)
No description available.
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Functional interactions of limbic afferents to the striatum and mesolimbic dopamine in reward-related processesBurns, Lindsay H. January 1991 (has links)
No description available.
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Development of hammerhead ribozymes against calretinin mRNA for use in transgenic miceEllis, Jonathan Henry January 1992 (has links)
No description available.
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Analysis of opioid- and gaba-induced inhibition in spinal slices from immature ratAllerton, Catherine Anne January 1989 (has links)
No description available.
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Adenosine 5'-triphosphate-sensitive potassium channels in the rat substantia nigraHicks, Gareth A. January 1994 (has links)
No description available.
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Chemical signalling in the basal ganglia : manipulation of dopamine neurotransmissionAugood, Sarah Jane January 1991 (has links)
The role of endogenous dopamine in mediating striatal preproenkephalin A, proneurotensin and preprosomatostatin gene expression in vivo was studied in monkeys treated with the catecholamine neurotoxin MPTP, and in rats treated acutely with selective dopamine D1 and D2 receptor antagonists. The effect on striatal neuropeptide gene expression were assessed by in situ hybridisation. The effect of MPTP treatment on the striatal content of substance P-like immunoreactivity was also studied by quantitative immunocytochemistry. Chronic MPTP treatment resulted in a significant loss (> 90&37) of tyrosine hydroxylase mRNA-containing cells in the ipsilateral substantia nigra pars compacta and ventral tegmental area; an increase in preproenkephalin A gene expression; and a decrease in the tissue content of substance P-like immunoreactivity in the ipsilateral striatum. Selective blockade of D2 receptors in rats also resulted in an increase in preproenkephalin A gene expression, whereas blockade of D1 receptors reduced expression of this gene, hence it appears that the dominant action of endogenous dopamine on preproenkephalin gene expression is via D2 receptors. Acute dopamine receptor blockade has different effects on other peptide genes in the striatum: proneurotensin gene expression was activated following D2 but not D1 receptor blockade, while preprosomatostatin gene expression was attenuated following blockade of either receptor subtype. The coupling of receptor activation to gene expression was studied by treatment of rats with pertussis toxin, which irreversibly ribosylates membrane Gi/o proteins. Microinjection of pertussis toxin into the striatum led to an increase in expression of both proneurotensin and preproenkephalin A genes, consistent with the hypothesis that Gi/o proteins mediate the effects of D2 receptor activation on striatal enkephalin and neurotensin cells.
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The contribution of the amygdaloid complex to the socio-sexual behaviour of the male ratMcGregor, Alison January 1991 (has links)
No description available.
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An electrophysiological investigation into the development and allosteric modulation of the NMDA-receptor-channel complex in the rat striatumSprosen, Timothy Simon January 1990 (has links)
No description available.
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The functional organisation of forebrain serotonin systemsHarrison, Amanda Ann January 1995 (has links)
No description available.
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Time-dependent changes in the neural systems underlying imprinting in the domestic chickDavey, Jane Elizabeth January 1988 (has links)
No description available.
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