Graphical models use Markov properties to establish associations among dependent variables. To estimate spatial correlation and other parameters in graphical models, the conditional independences and joint probability distribution of the graph need to be specified. We can rely on Gaussian multivariate models to derive the joint distribution when all the nodes of the graph are assumed to be normally distributed. However, when some of the nodes are discrete, the Gaussian model no longer affords an appropriate joint distribution function. We develop methods specifying the joint distribution of a chain graph with both discrete and continuous components, with spatial dependencies assumed among all variables on the graph. We propose a new group of chain graphs known as the generalized tree networks. Constructing the chain graph as a generalized tree network, we partition its joint distributions according to the maximal cliques. Copula models help us to model correlation among discrete variables in the cliques. We examine the method by analyzing datasets with simulated Gaussian and Bernoulli Markov random fields, as well as with a real dataset involving household income and election results. Estimates from the graphical models are compared with those from spatial random effects models and multivariate regression models. / Graduation date: 2013

In this thesis we describe subclasses of a class of graphs with three types of edges, called loopless mixed graphs (LMGs). The class of LMGs contains almost all known classes of graphs used in the literature of graphical Markov models. We focus in particular on the subclass of ribbonless graphs (RGs), which as special cases include undirected graphs, bidirected graphs, and directed acyclic graphs, as well as ancestral graphs and summary graphs. We define a unifying interpretation of independence structure for LMGs and pairwise and global Markov properties for RGs, discuss their maximality, and, in particular, prove the equivalence of pairwise and global Markov properties for graphoids defined over the nodes of RGs. Three subclasses of LMGs (MC, summary, and ancestral graphs) capture the modified independence model after marginalisation over unobserved variables and conditioning on selection variables of variables satisfying independence restrictions represented by a directed acyclic graph (DAG). We derive algorithms to generate these graphs from a given DAG or from a graph of a specific subclass, and we study the relationships between these classes of graphs. Finally, a manual and codes are provided that explain methods and functions in R for implementing and generating various graphs studied in this thesis.