Aim: To use the extraoral scanner 3D Sense in practice and compare the measurements on scanned material with conventional, direct clinical measurements. This is to evaluate if extraoral scanning can replace a clinical examination and extraoral 2D photography. Material & method: Fifteen adults at the Faculty of Odontology were recruited for the study. Five determined landmarks were marked in the faces of the subjects. Direct clinical measurements were performed between the landmarks of every subject and used as a reference. The subjects' faces were scanned and the same distances were measured in the scans. Differences in measurements of the two methods were conducted in a paired t-test. Intra- and inter operator differences were calculated for all distances. Intraclass correlations were used to describe to what extent subjects in the same group resemble each other.  Results: Conformity of direct clinical measurements and measurements on scanned material varied between the mean difference of 0,22-5,13 mm. Intra- and inter operator ICC was overall excellent. Conclusion: The measurements between the landmarks pronasale (prn) and pogonion (pg) was the only distance with no statistical significant difference between the two methods. The 3D Sense shows decreasing conformity to clinical measurements with increasing distances. Inter operator ICC shows excellent values and measuring on scanned material can be regarded as a reproducible method. The results indicate clinical acceptance for use of 3D Sense for some purposes in odontology. 3D Sense has been validated in-vitro and analyzed in-vivo. The studies have established the 3D Sense’s adequacy in odontology.