<p dir="ltr">Activity-based anorexia (ABA) is a rodent model of anorexia nervosa (AN) that induces several key components of AN, including voluntary reduction in food intake, reduced body weight, hyperactivity, and alterations to the hypothalamic-pituitary-adrenal (HPA) axis. Experiencing ABA during adolescence also effects behavior in social contexts, including contributing to the development of social avoidance even after cessation of exposure to the paradigm and restoration of weight lost during ABA. We used the social partition (SPT), novelty suppressed feeding (NSF), marble burying, and elevated plus maze (EPM) tests to determine the effects of two bouts of adolescent ABA on anxiety-like behavior in weight restored young adult female rats. One-way ANOVA analyses showed that two bouts of adolescent ABA contribute to prolonged increases in general and social avoidance in young adult female rats compared with control rats. To explain our behavioral findings, we next explored the effects of two bouts of adolescent ABA on glial fibrillary acidic protein (GFAP) and corticotropin-releasing hormone receptor 1 (CRFR1) expression in the oval bed nucleus of the stria terminalis (_ovBNST), a brain region involved in anxiety and social behavior. While previous research shows that two bouts of adolescent ABA contribute to HPA axis hyperactivation and _ovBNST inflammation following weight restoration from adolescent ABA, our one-way ANOVA analyses showed no significant differences in GFAP or CRFR1 expression in the _ovBNST across groups. Finally, to explore whether adolescent AN symptoms can predict anxiety in young adult women, we had female university students complete retrospective surveys of adolescent food restriction, eating disorder symptoms (EDEQ), and physical activity, as well as retrospective surveys of worry, behavioral inhibition, childhood adversity, and parental style. Using these variables, we created four adolescent predictor models: 1 (EDEQ; physical activity), 2 (restrictive eating; physical activity), 3 (EDEQ; physical activity; worry; behavioral inhibition; childhood adversity; and parental style), and 4 (restrictive eating; physical activity; worry; behavioral inhibition; childhood adversity; and parental style), which we regressed onto participants’ current generalized anxiety, fear of food, social avoidance, obsessions, compulsions, social physique anxiety, compulsive physical activity, and perceived stress scores. Regressing each predictor model onto these variables revealed that predictor model 1 better predicted and accounted for more variance in all anxiety types compared with predictor model 2. Moreover, predictor model 1 accounted for the most variance in fear of food and social physique anxiety compared with all anxiety types. Finally, predictor models 3 and 4 explained the most additional variance in generalized anxiety and social avoidance compared with all anxiety types. Cumulatively, our data suggest that, while adolescent eating disorder signs and symptoms predict several anxiety types in female university students, the effects of two bouts of ABA during adolescence on anxiety-like behavior in weight restored female rats is limited to specific anxiety-provoking stimuli.</p>

O objetivo deste trabalho visa compreender a experiência de ser-si-mesmo e ser-com em situação conjugal na contemporaneidade. Para compreender tal paisagem subjetiva, discutem-se os processos de subjetivação dominantes em nossa cultura, sob a ética da eficácia e do consumo do sujeito individualista. As relações sociais e conjugais nesse cenário preocupam psicólogos clínicos e sociais por modos coisificantes de ser, exclusores de diferença: o ser-si-mesmo e o ser-com o outro têm sofrido tensão pois a individualização gera uma ruptura no modo de ser-com. Para compreender essa experiência, foram entrevistados três casais em modos diversos de situação conjugal. A interpretação seguiu o método da Analítica do Sentido. Percebe-se que cada casal apresenta seu modo próprio de compreensão de ser-com em situação conjugal. Uma compreensão do modo de ser humano, pelo recorte da situação conjugal poderia empreender-se como: ser entre tensão. A conjugalidade pode ser caracterizada por uma oscilação maior ou menor entre momentos de fusão e momentos de diferenciação entre os parceiros. Apontando, também, um bem estar como sendo a direção do sentido de estar com o outro. Essa elaboração de experiência pelos participantes possibilitou o encaminhamento de articulação entre a dimensão existencial da clínica e a cultura no modo de ser do homem contemporâneo como ser-no- mundo-com-outros sendo si mesmo. Neste sentido, talvez seja essa a contribuição deste trabalho: introduzir o diferente, como possibilidade de encontrar-se, pelo coletivo, como alteridade / This work aims to comprehend the experience of being oneself and being with in conjugal situation in the contemporaneous world. To articulate a possible comprehension such subjective landscape, we discuss the dominant processes in our culture to constitute the subjectivity, taking into account the individualistic subjects ethics of efficacy and of consume. The social and conjugal relationships in such scenery are a critical preoccupation among clinical and social psychologists; they are concerned by the modes of being as a thing, which promote exclusion of difference: being oneself and being with other have been suffering tension by the individualization which creates a rupture in the mode of being with. To reflect upon that experience, three couples, living different modes of conjugal situation, were interview. The interpretation followed the Analytical of Sense Method. Each couple presented his own proper comprehension mode for being with in conjugal situation. A comprehension of the mans mode of being, by the scrap in conjugal situation would be undertake like being among tension. The conjugality could be characterized by wobbliness least or minor among moments of fusion and moments of differentiation between the couples. Also pointing to a well being as the sense direction to be with the other. The participants elaboration of experience made possible to show how culture articulates with a clinical existential dimension and the culture towards the contemporaneous mans mode of being as being-in-the world- with-others by being oneself. The contribution of this work is introduce the difference like possibility by being oneself including the collective and the others

Made available in DSpace on 2017-06-01T18:08:32Z (GMT). No. of bitstreams: 1 claudine alcoforado.pdf: 1203114 bytes, checksum: 1f67bbb445b114e6a8db30dcbdfa91fb (MD5) Previous issue date: 2005-04-15 / This work aims to comprehend the experience of being oneself and being with in conjugal situation in the contemporaneous world. To articulate a possible comprehension such subjective landscape, we discuss the dominant processes in our culture to constitute the subjectivity, taking into account the individualistic subject s ethics of efficacy and of consume. The social and conjugal relationships in such scenery are a critical preoccupation among clinical and social psychologists; they are concerned by the modes of being as a thing, which promote exclusion of difference: being oneself and being with other have been suffering tension by the individualization which creates a rupture in the mode of being with. To reflect upon that experience, three couples, living different modes of conjugal situation, were interview. The interpretation followed the Analytical of Sense Method. Each couple presented his own proper comprehension mode for being with in conjugal situation. A comprehension of the man s mode of being, by the scrap in conjugal situation would be undertake like being among tension. The conjugality could be characterized by wobbliness least or minor among moments of fusion and moments of differentiation between the couples. Also pointing to a well being as the sense direction to be with the other. The participants elaboration of experience made possible to show how culture articulates with a clinical existential dimension and the culture towards the contemporaneous man s mode of being as being-in-the world- with-others by being oneself. The contribution of this work is introduce the difference like possibility by being oneself including the collective and the others / O objetivo deste trabalho visa compreender a experiência de ser-si-mesmo e ser-com em situação conjugal na contemporaneidade. Para compreender tal paisagem subjetiva, discutem-se os processos de subjetivação dominantes em nossa cultura, sob a ética da eficácia e do consumo do sujeito individualista. As relações sociais e conjugais nesse cenário preocupam psicólogos clínicos e sociais por modos coisificantes de ser, exclusores de diferença: o ser-si-mesmo e o ser-com o outro têm sofrido tensão pois a individualização gera uma ruptura no modo de ser-com. Para compreender essa experiência, foram entrevistados três casais em modos diversos de situação conjugal. A interpretação seguiu o método da Analítica do Sentido. Percebe-se que cada casal apresenta seu modo próprio de compreensão de ser-com em situação conjugal. Uma compreensão do modo de ser humano, pelo recorte da situação conjugal poderia empreender-se como: ser entre tensão. A conjugalidade pode ser caracterizada por uma oscilação maior ou menor entre momentos de fusão e momentos de diferenciação entre os parceiros. Apontando, também, um bem estar como sendo a direção do sentido de estar com o outro. Essa elaboração de experiência pelos participantes possibilitou o encaminhamento de articulação entre a dimensão existencial da clínica e a cultura no modo de ser do homem contemporâneo como ser-no- mundo-com-outros sendo si mesmo. Neste sentido, talvez seja essa a contribuição deste trabalho: introduzir o diferente, como possibilidade de encontrar-se, pelo coletivo, como alteridade