Despite being safe and effective, human papillomavirus (HPV) vaccination rates are lower than other recommended adolescent vaccines. CDC recommends catch-up vaccination for all persons through age 26 years if not adequately vaccinated when younger making college campuses an important site for catch-up vaccination programs. The project is a quality improvement project being implemented on a public southeastern college campus. The campus health services clinic is the setting for the practice change. Aims: The overall purpose of the QI project is to enhance usage of current CDC HPV recommendations and increase campus population awareness of HPV. Processes: The project received a “Determination of Not Human Subjects Research” from the ETSU Human Research Protection Program. Staff in-service detailing the practice change for routine HPV vaccine status assessment and promotion of HPV vaccination, based on CDC HPV recommendations. Digital-based HPV education materials are being shared with both health services and the student wellness ambassador group. The ambassador group will share items with the campus community via social media and flyers. An optional, anonymous survey will be available when accessing the digital HPV content. De-identified chart audit data will be monitored to assess adoption of the practice change. Nonidentifiable digital access data will be used to assess usage of the educational materials. Results: The final results of the QI project will not be available. Preliminary descriptive statistics will be presented. Limitations: The vaccine isn’t available on campus and the electronic health record lacks directed HPV vaccine assessment on most visit forms. Conclusions: The preliminary conclusions and impact will be presented.