To aid in understanding headache etiology and symptomatology, psychological and physiological variables were examined in patients with migraine and combination headaches (combined migraine and muscle-contraction headaches). One hundred patients being evaluated for treatment of their headaches at The New England Center for Headache participated in this study. They were assigned to the migraine or combination group, based on diagnoses made by three headache specialists—a psychologist, a psychiatrist, and a nuerologist. Personality data from the MMPI and frontalis electromyographic readings reflecting muscle tensions across three stimulus conditions were compared between the two groups. Subjects were also asked to rate the perceived level of stress elicited by the three conditions.