Cobalt 60 (Co-60) radiation therapy is a simple and reliable method of treating cancer by irradiating treatment volumes within the patient with high energy gamma rays. Medical linear accelerators (linacs) began to replace Co-60 units during the 1960’s in more developed countries, but Co 60 has remained the main source of radiotherapy treatment in less developed countries around the world. As a result, technological advancements made in more developed countries to deliver more precise radiation treatment that improves patient outcome have not been clinically applied to Co-60 machines. The medical physics group at the Cancer Centre of Southeastern Ontario has shown that these same technological advancements can be applied to Co-60 machines which would increase the accessibility of these modern improvements in radiotherapy treatment. However, for these modern treatments to improve patient outcome they require more precise localization of the patient prior to therapy. In more developed countries, this is currently provided by comparing computed tomography (CT) used for treatment planning with images acquired on the linac immediately before treatment. In the past decade, cone-beam CT (CBCT) has been developed to provide 3D CT images of the patient immediately prior to treatment on a linac. This imaging modality would also be ideal for patient localization when conducting modern Co-60 treatments since it would only require the addition of an imaging panel to produce CBCT images using the Co-60 source. A prototype Co-60 CBCT imaging system was implemented and characterized. Image noise, contrast, spatial resolution, and artifacts were studied. Algorithms to reduce the image artifacts were implemented and found to improve perceived image quality. The imaging system was found to have a ~1.8 mm high-contrast spatial resolution and the ability to detect 3 cm low-contrast soft-tissue structures in water. Anthropomorphic phantoms were also imaged and the observed anatomy in Co-60 CBCT images was comparable to kilovoltage CT. These results are comparable to clinically relevant linac-based CBCT using high energy X rays of similar energies to Co-60 gamma rays. This suggests that Co-60 CBCT should be able to provide the necessary images to localize patients for modern Co-60 radiation treatments. / Thesis (Master, Physics, Engineering Physics and Astronomy) -- Queen's University, 2010-11-30 13:40:07.61

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This masters thesis analyzes telecommunications policies in Argentina, Brazil, Paraguay and Uruguay, and relates these to the ongoing economic integration of these countries within MERCOSUR. To this end, a survey of the telecommunications sector in each of the MERCOSUR countries, depicting the main features of their respective regulatory framework, competition policy, and universal service goals is provided in Part II. Part III briefly describes the GATS/BTA framework and comments on MERCOSUR countries' commitments towards market liberalization. In Part IV, MERCOSUR's legal and institutional framework, along with the common initiatives that have been taken with respect to the telecommunications sector, are considered. By way of conclusion, Part V proposes further reflections on theoretical approaches aimed at framing telecommunications normativity in consideration of its dynamic interaction with globalization and integration in the context of MERCOSUR.

Latin American literary criticism has traditionally underestimated the significance of the Gothic aesthetic, in spite of the rich Gothic literary tradition of Latin America. Specifically in the Southern Cone - the focus of my research - there is a particular recurrence and consumption of this genre, not only in literature but also in cinema, which has not been deeply analyzed. I argue that a close examination of the Gothic and Fantastic elements in these novels and films unveils anxieties, repressions and manifestations of social decay that underlie common codes of social decency and the conventions of maintaining an oppressive social tradition. My analysis of particular novels extends from the beginning of the twentieh-century through the Boom; my discussion then extends to film productions from the 1960s to the present. In the first chapter I explore the dissemination of Gothic figures and forms from their eighteenth-century origins to the present. In the second chapter I discuss how the Gothic aesthetic was used at the beginning of the twentieth-century to comment on the effects of modernization and scientific/psychological discoveries in the Southern Cone. I also analyze the Gothic as a powerful feminist discourse. Chapter three focuses on the way the Gothic aesthetic is employed as a mechanism to communicate social and moral decay in a typical Southern Cone family. I also explore how the Gothic is used to question a political-social repression or a dictatorship. In chapter four I focus on cinema in an aesthetically and technically diverse selection of filmes. All of them employ vampirism to comment on different sexual issues, such as repression, incest, homosexuality, fetishism, sadism, and other sexual-social taboos. Finally, the conclusion demonstrates that, while the Gothic aesthetic maintains certain constants throughout the twentieth-century, its underlying meaning shifts to reflect the dominant political-social themes of each era, thus ensuring its continued relevance to popular audiences.

Geotechnical engineering design has relied upon deterministic methods of analysis whereby values for analysis parameters and conditions are selected subjectively based on judgment with the intent of providing acceptable margins of safety. The objective of this research was to improve the use of probabilistic slope stability analysis in practice so that the design of slopes can be made on a consistent and probabilistic basis. The current research involved the development of a methodology for the measurement and modeling of the anisotropic autocorrelation distance of cohesive soils, which was demonstrated at Dyke 17 West of the McArthur Falls Generating Station. In-situ testing using the piezocone and laboratory testing was conducted to characterize the spatial variability of the effective-shear strength envelope. Vertical (down-hole) and horizontal (cross-hole) geostatistical analysis was conducted to assess the anisotropy of the semivariogram. The investigation identified that heterogeneous inclusions had significant impacts on the results, but that simplistic (visual) identification and filtering procedures were adequate. The effective-stress shear strength envelope was statistically characterized as a random field, which was simulated as a first-order Markov process using customized add-in functions in a limit-equilibrium slope stability analysis. The analysis accounts for the spatial variability of shear strength and is capable of simulating both isotropic and anisotropic autocorrelation functions. The study showed that the critical slip surface geometry and the probability of failure can be significantly different when the anisotropy of spatial correlation is accounted for. The study also showed that neglecting spatial correlation may over-estimate the probability of failure, however this finding was noted to be likely case-specific. The primary conclusion of the study was that appropriate representation of spatial correlation is essential to calculating the probability of failure. Finally, convergence of the probabilistic simulation was evaluated using bootstrapping of the simulated factor of safety distribution to assess the standard error in the mean factor of safety, standard deviation of factor of safety and the probability of failure. A convergence criterion based on the percentage standard error in the probability of failure was proposed and used to define the number of Monte-Carlo iterations required.

The ignition and subsequent burning of polyurethane foam based mattresses poses a significant danger to life and safety in North American homes. The development of fire models which can predict the full scale fire behavior of these mattresses using bench scale data would assist manufacturers and regulators to manage this danger in a cost effective manner. This thesis builds on previous work by the University of Saskatchewan and University of Waterloo fire research groups and focuses on the evaluation of one such scaling model, which was originally developed during the Combustion Behavior of Upholstered Furniture (CBUF) project. The evaluation of the CBUF model conducted in this thesis isolates the heat release rate (HRR) density sub-model and explores the effects of 1) cone calorimeter incident heat flux setting, 2) specimen thickness and 3) ignition location on the predictive capability of the CBUF model. To provide input for the CBUF model cone and furniture calorimeter tests were conducted. Cone calorimeter tests were conducted on foam specimen thicknesses of 2.5, 5.0, 7.5 and 10.0 cm at incident heat flux settings of 25, 35, 50 and 75 kW/m2. Furniture calorimeter tests were conducted on foam specimen thicknesses of 2.5, 5.0, 7.5 and 10.0 cm in both edge and center ignition configuration. Flame area spread rates were measured from infrared video of the furniture calorimeter tests using an automated algorithm. It was found that HRR curves predicted by the CBUF model showed good agreement with experimental results. Experimental results from tests of thinner foams were predicted with greater success than results from thicker foams, and results from edge ignition tests were predicted with greater success than results of center ignition tests. The results of this study indicated that specimen thickness and ignition location need to be considered when selecting an appropriate incident heat flux setting for producing input data for the CBUF model.

In this thesis, multidimensional signal processing techniques to mitigate disturbances in synthetic aperture systems such as radio telescopes are investigated. Here, two computationally efficient three-dimensional (3D) spatio-temporal (ST) finite impulse response (FIR) cone filter bank structures are proposed. Furthermore, a strategy is proposed to design 3D ST FIR frustum filter banks, having double-frustum-shaped passbands oriented along the temporal axis, derived from appropriate 3D ST FIR cone filter banks. Both types of cone and frustum filter banks are almost alias free and provide near-perfect reconstruction. In the proposed cone and frustum filter banks, both temporal and spatial filtering operations can be carried out at a significantly lower rate compared to previously reported 3D ST FIR cone filter banks implying lower power consumption. Furthermore, the proposed cone and frustum filter banks require a significantly lower computational complexity than previously reported 3D ST FIR cone and frustum filter banks. Importantly, this is achieved without deteriorating the improvement in signal-to-interference-plus-noise ratio. A theoretical analysis of brightness distribution (BD) errors caused by parameter perturbations and mismatches among the transfer functions of receivers employed in synthetic aperture systems is presented. First, the BD errors caused by perturbations in the transfer functions of low noise amplifiers (LNAs) and anti-aliasing filters (AAFs) are considered, and the characteristics of the additive BD error and its effects on synthesized BDs are thoroughly analyzed. Second, the conditions that should be satisfied by the transfer functions of digital beamformers to eliminate the BD errors caused by their phase responses are examined. The sufficient condition to eliminate the BD errors is that the transfer functions are matched, and, interestingly, the phase responses are not necessary to be linear. Furthermore, the BD errors caused by typical tolerances of passive L and C elements used to implement the AAFs and those caused by the random variations of gain from LNA to LNA are quantified through numerical simulations. The simulations indicate that substantial BD errors are observed at frequencies that are close to the passband edge of the AAFs. / Graduate

The cone pressuremeter is an in situ testing device comprising a pressuremeter mounted behind a cone penetrometer of the same diameter. Previously reported tests had indicated that the cone pressuremeter can provide measurements of soil strength, stiffness and in situ stress. The study presented in this thesis is aimed at developing methods of interpretation of the cone pressuremeter that can be applied with confidence to a variety of soil types. Carbonate sands have been the cause of significant problems associated with the design of foundations for offshore structures. A programme of cone pressuremeter testing in a carbonate sand from the west coast of Ireland is presented. Tests were carried out in a calibration chamber where conditions of vertical and horizontal stress and relative density were controlled. The influence of these parameters on measured values of cone resistance and pressuremeter limit pressure is assessed. Similar tests were also carried out in a felspathic sand, and correlations have been presented for deriving horizontal stress and relative density that are applicable to most types of sand. The influence of creep strains and of overconsolidation were other features of carbonate sand that have been assessed with the cone pressuremeter. A numerical model which accounts for the crushing characteristics of carbonate sand is presented, and is shown to improve significantly predictions of limit pressure measured in the calibration chamber. Cone pressuremeter tests were carried out in soft clay at the Bothkennar test site in Scotland. An analysis based upon cavity expansion theory was shown to provide good estimates of undrained shear strength and stiffness compared with results from other in situ and laboratory tests. Estimates of the in situ horizontal stress were found to be unrealistically high. Shear modulus in both sand and clay has been measured from unload-reload cycles carried out during pressuremeter expansion. The stress levels and strain amplitudes of these cycles have been shown to influence the shear modulus greatly. In sand, a procedure for relating these moduli to those at an extremely small reference strain is presented. In clay, shear moduli are shown to give a remarkably close agreement to others reported from Bothkennar, when due account of the strain amplitude is made. Finally, a time/cost analysis between the cone pressuremeter, the cone penetrometer and the self-boring pressuremeter is presented. The cone pressuremeter is found to be a cost-effective device bearing in mind the amount and quality of information it can provide.