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Multiple potential well structure in inertial electrostatic confinement devicesMeyer, Ryan, January 2004 (has links)
Thesis (M.S.) University of Missouri-Columbia, 2004. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file viewed on (June 30, 2006) Vita. Includes bibliographical references.
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Operating characteristics of disc focus dense plasma /Puttarudraiah, Sathyavathiamma Magadi January 1970 (has links)
No description available.
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A Design Thesis: Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Hemodialysis CentresKosa, Sarah Daisy January 2014 (has links)
Background: As part of this thesis work, we developed a Shower Technique protocol (‘STP’) for hemodialysis patients with healed central venous catheter (catheter) exit sites, designed to permit showering but not increase infection risk.
Research question: Is it feasible to conduct a randomized control trial called the Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Centres (HIPPO SAT) study comparing the rate of CRB in adult satellite hemodialysis patients using STP versus standard catheter care alone with 6 month follow up?
Study Design: The HIPPO SAT pilot study is a multi-centre randomized control trial. Eligible participants will be randomized to STP versus standard care after meeting predefined criteria to confirm healed tunneled catheter exit site.
Primary Outcome: Feasibility will be determined based on 5 outcome measures: accuracy of the CRB rate documentation in the satellite setting, and percentage of patients screened, recruited, educated successfully in the STP (intervention arm), and using aspects of STP (% of contaminated patients in the control arm).
Study Setting: In satellite units affiliated with 2 academic and 3 community centres in south central Ontario, Canada.
Patient Population: Adult satellite Hemodialysis patients dialyzing via catheter with healed catheter exit sites.
Intervention: STP and standard catheter care; or Control: standard catheter care;
Analysis: Each measure of feasibility has its statistical threshold for success. If the threshold is reached in 4 of the 5 measures, the full HIPPO SAT study will be deemed feasible.
Discussion: A pilot feasibility study of the larger study is critical due to the potential challenges associated with recruitment, compliance and contamination. / Thesis / Master of Science (MSc)
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Delivery of a coated bioactive from a rumen controlled-release deviceSyzov, Vladyslav. January 2008 (has links)
Thesis (M.E.)--University of Waikato, 2008. / Title from PDF cover (viewed September 18, 2008) Includes bibliographical references (p. 66-70)
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The development and assessment of both a separate, once-daily modified release matrix formulation of metoprolol tartrate and a combination formulation with hydrochlorothiazideArjun, Jessica January 2001 (has links)
The use of controlled release dosage forms has increased significantly in recent years as they result in increased patient compliance and higher therapeutic efficiency. This research focused on the development of a once daily dosage form that could be used for the treatment of hypertension. Both a separate sustained release dosage of metoprolol tartrate and a combination dosage form that included both an immediate release hydrochlorothiazide and a sustained release metoprolol component, were developed and evaluated. A matrix tablet, consisting of an ethylcellulose ranulation of metoprolol tartrate compressed into a hydrophilic hydroxypropyl methylcellulose polymer matrix, effectively sustained metoprolol release over a 22-hour experimental period. A multiparticulate combination dosage form that consisted of six coated mini matrix tablets of metoprolol and a powder blend of hydrochlorothiazide packed into a gelatin capsule, displayed zero order release kinetics for metoprolol release over 22 hours (r2=0.9946). The release of hydrochlorothiazide was found to be comparable to that of a commercially available product tested. Differential Scanning Calorimetry was used to identify possible incompatibilities between MPTA and excipients initially, and long term stability testing was used to assess to behaviour of the dosage form. Dissolution testing of the dosage forms was performed using USP Apparatus III, which was found to be more discriminating between the batches assessed. Dissolution curves were evaluated for similarity and difference using f1 and f2 fit factors. Samples were analyzed using a high performance liquid chromatographic method that was developed and validated for the simultaneous determination of the compounds of interest. Various factors influencing drug release from the developed dosage forms were assessed and recommendations for further optimization of the formulation are made. Factors evaluated included the quantity of granulating fluid, matrix polymer content, drug load and process variables, including drying time and compression force. The influence of various coating levels on drug release was assessed and none of the levels assessed were found to adequately retarded drug release over a 22-hour period. Combinations of tablets coated to different levels allowed for the successful development of a sustained release metoprolol component, which could be included into the combination dosage form.
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The Value of Controlled Substance Destruction in Long Term Care FacilitiesChillion, Lindsey January 2006 (has links)
Class of 2006 Abstract / Objectives: To determine the economic impact of controlled substance destruction in multiple long term care facilities in Southern Arizona and to identify related demographic characteristics of the patients and facilities.
Methods: Subjects had controlled substance prescriptions destroyed at nursing homes serviced by a pharmacy nursing home provider in Tucson, Arizona. Controlled substances destruction records and existing prescription records were reviewed and data was collected on the name, strength, number of units destroyed, date of destruction and schedule of each controlled medication that was destroyed for a particular patient over the course of a year. Demographic data was collected on patient gender, age, type of insurance coverage and the size of the nursing home facilities.
Results: A total of 1095 controlled substance prescriptions were destroyed during the time period of the study and the total cost of destroyed medication was $26,886.37. The average cost of destroyed medication per prescription was $24.55 ± 60.38 (mean ± SD). Schedule II controlled substances accounted for the highest total cost per prescription destroyed and destruction of unused controlled substances cost indigent insurance programs more than any of the other payers studied. There was no difference in mean cost per prescription destroyed by facility, therapeutic class or between women and men. Conclusions: The value of controlled substance destruction in long term care facilities is sizeable. To reduce waste, prescribers and pharmacy providers should initially dispense moderate quantities of controlled substances until it is apparent that the medication is tolerable and efficacious for the patient.
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A SELF TUNING PHASE-LOCKED LOOPHardwicke, K. R. 10 1900 (has links)
International Telemetering Conference Proceedings / October 26-29, 1992 / Town and Country Hotel and Convention Center, San Diego, California / The uncertainty in the gain of voltage controlled crystal oscillators (VCXOs) used in the
implementation of certain analog phase-locked loops (PLLs) suggests some form of
automatic tuning algorithm, both for pretuning and during operation. This paper proposes
an adaptive PLL (APLL) algorithm to fill this need for PLLs used in the recovery of tones
in noise. This algorithm makes use of a resonant error algorithm to remove the effects of
VCXO noise, measurement noise, and parasitic poles. Both classical convergence
theorems and robustness theorems that indicate the functionality of the proposed algorithm
are given. Finally, the implementation of this algorithm is considered.
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Factors influencing formation and the in vitro drug release from pellets containing chitosanQuigley, Karen Josephine January 1994 (has links)
No description available.
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Evaluation of binding agents for the preparation of spherical granules by extrusion/spheronisationKnight, Paul Edward January 1993 (has links)
No description available.
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Influence of process variables on the preparation of spherical granulesChapman, Stephen Robert January 1985 (has links)
No description available.
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