Two studies were conducted to evaluate cotton gin mote as a forage replacement by determining nutrient digestibility and nitrogen and energy retention. Three diets were used: 0%, 50%, and 100% mote. Dry matter intake was greatest for steers consuming 100% mote. Digestibility of DM, OM, CP, and energy was least for steers consuming 50% mote and greatest for those consuming 0% mote. Digestibility of NDF and ADF was greatest for steers consuming 0% mote. Fat digestibility was greatest by steers consuming 0% mote and least by steers consuming 100% mote, with those consuming 50% mote being intermediate. Steers consuming 0 and 50% mote retained less protein and energy than those consuming 100% mote. In trial 2, IVDMD of cotton gin mote was evaluated to determine rate of disappearance of DM, CP, NDF, and ADF. The 0% mote diet revealed the greatest rate of disappearance for DM, CP, NDF, and ADF, followed by the 50% and 100% mote diet, respectively.