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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
81

Import of chimeric proteins into plant mitochondria

Mahe, Laetitia. January 2001 (has links)
No description available.
82

Construction of a single-chain antibody against intermediate filaments

Rutherford, Sharon Ann January 1994 (has links)
No description available.
83

The expression of neurofilament protein and mRNA levels in the lateral geniculate nucleus and area V1 of the developing and adult vervet monkey (Ceorcopithicus aethiops) /

Kogan, Cary. January 1999 (has links)
No description available.
84

Phospho-Regulation of Actin Organization and Endocytosis in Yeast by the PP1 Targeting Protein Scd5p

Chang, Ji Suk January 2005 (has links)
No description available.
85

Identification and Characterization of New and Distinct Functional Roles of Posttranscriptional Control Elements in Cytoplasmic Expression of Retroviral RNA

Hull, Stacey Lynn 20 December 2002 (has links)
No description available.
86

Compounds and Methods to Study O-GlcNAc Modification of Proteins

Zheng, Hongchao 08 1900 (has links)
<p> A variety of important cell functions rely on O-GlcNAcylation of proteins, a kind of post-translational glycosylation that modifies nuclear and cytoplasmic proteins on serine or threonine residues by the addition of the single sugar moiety β-N-acetylglucosamine (O-GlcNAc). Generally, two enzymes can catalyze the formation and cleavage of the O-GlcNAc O-glycosidic linkage. The O-GlcNAc transferase (OGT) catalyzes the transfer of N-acetylglucosamine from uridine diphosphate N-acetylglucosamine to the hydroxyl group of specific Thr and Ser residues. On the other hand, hydrolysis of the sugar moiety from proteins is achieved via the bi-functional nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT). Since O-GlcNAcylation plays very important roles in many cell processes such as transcription, translation and protein-protein interaction, my research mainly focused on preparing compounds and developing methods to study the O-GlcNAcylation process and discover the structural information of OGT and NCOAT.</p> <p> In this thesis, the important enzyme substrates (YSDSPSTST for OGT and YSDSP(O-GlcNAc-Ser)TST for NCOAT) were prepared by solid phase synthesis and purified by preparative reverse phase HPLC. Their structure and sequence were confirmed by ESI-MS and tandem MS (MS/MS). The building block S-GlcNAc-Ac3-Ser-COOBn for preparing S-GlcNAcylated peptides was prepared by a multistep procedure. Two potent photoaffinity labeled probes for mapping the active site of sOGT were designed and synthesized, and their IC50 values for sOGT were measured by CapLC and a beta-elimination method. Also, many analytical methods were developed for studying the O-glcNAcylation, including discovering the O-Glycosylation site of peptides by MS/MS and beta-elimination methods, sequencing peptides by MS/MS, analyzing the protein digests by CapLC-MALDI MS and studying the ion mobility of peptides and glycopeptides using ion mobility spectrometry.</p> / Thesis / Master of Science (MSc)
87

The role of TUDOR in Drosophila polar granule assembly and germ cell formation

Thomson, Travis. January 1900 (has links)
Thesis (Ph.D.). / Written for the Dept. of Biology. Title from title page of PDF (viewed 2008/07/24). Includes bibliographical references.
88

The function of the germline rna helicase (GLH) genes in caenorhabditis elegans

Kuznicki, Kathleen January 2000 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2000. / Typescript. Vita. Includes bibliographical references (leaves 107-112). Also available on the Internet.
89

Modulation of nuclear receptor function by interacting proteins /

Osman, Waffa, January 2007 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
90

Molecular cloning and characterization of the murine acyl-CoA thioesterase CTE-I /

Lindquist, Per J. G., January 2004 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 5 uppsatser.

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