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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Characterisation and trafficking of group I metabotropic glutamate receptor-green fluorescent protein chemicals

Coutinho, Victoria January 2001 (has links)
No description available.
12

Computational studies of structural properties of both calciumoxide and calcium suphide

Ramusi, Matome Jack January 2006 (has links)
Thesis (M.Sc. (Physics)) --University of Limpopo, 2006 / In this work, we are studying the properties of CaS and CaO structures in both atomistic simulation and Density Functional Theory. Defects formation (vacancies, impurity and interstitial) will be mechanism studied by using atomistic simulation method. In this approach, Mott-Littleton method will be used since it is a good ap- proach of defects studies, and further explanation will be given on how the introduction of defects contribute on the stability of the bulk material. Diffusion of different atoms from one lattice site via interstitial path to vacancy lattice site, and how it segregates through the material, is also part of this study. The surface properties will be studied using both methods mentioned. Surface energies calculations of different surface layers (e.g. CaS (100), CaS (110), CaS (111), CaO (100), CaO (110) and CaO (111)) is the approach we used to determine the most stable surface. In atomistic simulation, we further studied how percentage coverage of atoms contributes on the stability of the surfaces. We further used Density Functional Theory to calculate surface energies of the above-mentioned surfaces. As in atomistic simulation method, we used surface ener- gies to determine the most stable surface. In DFT we used only the most stable surface of both CaS and CaO to study the adsorption of molecules, namely H2O, H2S, HS and S2 on CaO (100) and CaS (100). The most/least-adsorbed molecule on both surfaces is explained in this study.
13

Is the Cytoskeleton Necessary for Viral Replication?

Morgan, Rachel E 09 July 2012 (has links)
The cytoskeleton plays an important role in trafficking proteins and other macromolecular moieties throughout the cell. Viruses have been thought to depend heavily on the cytoskeleton for their replication cycles. However, studies, including one in our lab, found that some viruses are not inhibited by anti-microtubule drugs. This study was undertaken to evaluate the replication of viruses from several families in the presence of cytoskeleton-inhibiting drugs and to examine the intracellular localization of the proteins of one of these viruses, Sindbis virus, to test the hypothesis that alternate pathways are used if the cytoskeleton is inhibited. We found that Sindbis virus (Togaviridae, positive-strand RNA), vesicular stomatitis virus (Rhabdoviridae, negative-strand RNA), and Herpes simplex virus 1 (Herpesviridae, DNA virus) were not inhibited by these drugs, contrary to expectation. Differences in the localization of the Sindbis virus were observed, suggesting the existence of alternate pathways for intracellular transport.
14

Gamma-irradiation protection of collagenous biomaterial derived from human bone.

Mnisi, Fikile Muriel. January 2012 (has links)
M. Tech. Biomedical Technology. / Aims to determine whether pure type collagen biomaterial gels can be protected from scission damage by the addition of different fractions from ColBio, resulting in successful cross-linking by g-irradiation.
15

Is the Cytoskeleton Necessary for Viral Replication?

Morgan, Rachel E 09 July 2012 (has links)
The cytoskeleton plays an important role in trafficking proteins and other macromolecular moieties throughout the cell. Viruses have been thought to depend heavily on the cytoskeleton for their replication cycles. However, studies, including one in our lab, found that some viruses are not inhibited by anti-microtubule drugs. This study was undertaken to evaluate the replication of viruses from several families in the presence of cytoskeleton-inhibiting drugs and to examine the intracellular localization of the proteins of one of these viruses, Sindbis virus, to test the hypothesis that alternate pathways are used if the cytoskeleton is inhibited. We found that Sindbis virus (Togaviridae, positive-strand RNA), vesicular stomatitis virus (Rhabdoviridae, negative-strand RNA), and Herpes simplex virus 1 (Herpesviridae, DNA virus) were not inhibited by these drugs, contrary to expectation. Differences in the localization of the Sindbis virus were observed, suggesting the existence of alternate pathways for intracellular transport.
16

Characterisation of the benzimidazole-binding site on the cytoskeletal protein tubulin /

MacDonald, Louisa M. January 2003 (has links)
Thesis (Ph.D.) --Murdoch University, 2003. / Thesis submitted to the Division of Veterinary and Biomedical Sciences. Includes bibliographical references (leaves 160-196).
17

Adaptive Control of an Optical Trap for Single Molecule and Motor Protein Research

Wulff, Kurt Daniel, January 2007 (has links)
Thesis (Ph. D.)--Duke University, 2007. / Includes bibliographical references.
18

Proteomics of the ovine cataract : a thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Lincoln University /

Muir, Matthew Stewart. January 2008 (has links)
Thesis (Ph. D.) -- Lincoln University, 2008. / Also available via the World Wide Web.
19

Caspase 6 comparison of activation between exogenously expressed caspase 6 in bacterial and mammalian cells, and identification of novel downstream substrates /

Klaiman, Guy. January 1900 (has links)
Thesis (Ph.D.). / Written for the Dept. of Neurology and Neurosurgery. Title from title page of PDF (viewed 2009/06/09). Includes bibliographical references.
20

Characterization of the cytosolic proteins involved in the amoeboid motility of ascaris sperm

Buttery, Shawnna Marie. Roberts, Thomas M., January 2003 (has links)
Thesis (Ph. D.)--Florida State University, 2003. / Advisor: Dr. Thomas M. Roberts, Florida State University, College of Arts and Sciences, Department of Biological Science. Title and description from dissertation home page (viewed Aug. 23, 2004). Includes bibliographical references.

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