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The statistical properties of training, validation and test data play an important role in assuring optimal performance in artificial neural networks (ANN). Re-searchers have proposed randomized data partitioning (RDP) and stratified data partitioning (SDP) methods for partition of input data into training, vali-dation and test datasets. RDP methods based on genetic algorithm (GA) are computationally expensive as the random search space can be in the power of twenty or more for an average sized dataset. For SDP methods, clustering al-gorithms such as self organizing map (SOM) and fuzzy clustering (FC) are used to form strata. It is assumed that data points in any individual stratum are in close statistical agreement. Reported clustering algorithms are designed to form natural clusters. In the case of large multivariate datasets, some of these natural clusters can be big enough such that the furthest data vectors are statis-tically far away from the mean. Further, these algorithms are computationally expensive as well. Here a custom design clustering algorithm (CDCA) has been proposed to overcome these shortcomings. Comparisons have been made using three benchmark case studies, one each from classification, function ap-proximation and prediction domain respectively. The proposed CDCA data partitioning method was evaluated in comparison with SOM, FC and GA based data partitioning methods. It was found that the CDCA data partitioning method not only performed well but also reduced the average CPU time. / Engineering Management