The Copper Creek thrust fault in the southern Appalachians places Cambrian over Ordovician sedimentary strata. The fault accommodated displacement of 15-20 km at 100-180 °C. Along the hanging wall-footwall contact, microstructures within a ~2 cm thick calcite and shale shear zone suggest that calcite, not shale, controlled the rheology of the shear zone rocks. While shale deformed brittley, plasticity-induced fracturing in calcite resulted in ultrafine-grained (<1.0 μm) fault rocks that deformed by grain boundary sliding (GBS) accommodated primarily by diffusion creep, suggesting low flow stresses. Optical and electron microscopy of samples from a transect across the footwall shale into the shear zone, shows the evolution of rheology within the shear zone. Sedimentary laminations 1 cm below the shear zone are cut by minor faults, stylolites, and fault-parallel and perpendicular calcite veins. At vein intersections, calcite grain size is reduced (to ~0.3 μm), and microstructures include inter-and-intragranular fractures, four-grain junctions, and interpenetrating boundaries. Porosity rises to 6 percent from <1 percent in coarse (25 μm) areas of calcite veins. In coarse-grained calcite, trails of voids follow twin boundaries, and voids occur at twin-twin and twin-grain boundary intersections. At the shear zone-footwall contact, a 350 μm thick calcite band contains coarseand ultrafine-grained layers. Ultrafine-grained (~0.34 μm) layers contain microstructures similar to those at vein intersections in the footwall and display no lattice-preferred orientation (LPO). Coarse-grained layers cross-cut grain-boundary alignments in the ultrafine-grained layers; coarse grains display twins and a strong LPO. Within the shear zone, ultrafine-grained calcite-aggregate clasts and shale clasts (5-350 μm) lie within an ultrafine-grained calcite (<0.31 μm) and shale matrix. Ultrafinegrained calcite (<0.31 μm) forms an interconnected network around the matrix shale. Calcite vein microstructures suggest veins continued to form during deformation. Fractures at twin-twin and twin-grain boundary intersections suggest grain size reduction by plasticity-induced fracturing, resulting in <1 μm grains. Interpenetrating boundaries, four-grain junctions, and no LPO indicate the ultrafine-grained calcite deformed by viscous grain boundary sliding. The evolution of the ultrafine-grain shear zone rocks by a combination of plastic and brittle processes and the deformation of the interconnected network of ultrafine-grained calcite by viscous GBS enabled a large displacement along a narrow fault zone.