The axial map of a town is one of the key components of the space syntax method – a tool for analysing urban layout. It is derived by placing the longest and fewest lines, called axial lines, to cross the adjacencies between convex polygons in a convex map of a town. Previous research has shown that placing axial lines to cross the adjacencies between a collection of convex polygons is NP-complete, even when the convex polygons are restricted to rectangles and the axial lines to have orthogonal orientation. In this document, we show that placing orthogonal axial lines in orthogonal rectangles where the adjacencies between the rectangles are restricted to be crossed only once (ALPSC- OLOR) is NP-complete. As a result, we infer the single adjacency crossing version of the general axial line placement problem is NP-complete. The transformation of NPcompleteness of ALP-SC-OLOR is from vertex cover for biconnected planar graphs. A heuristic is then presented that gives a reasonable approximate solution to ALP-SC-OLOR based on a greedy method.