The use of illicit drugs continues to be a problem around the world, particularly in the United States. Many individuals relapse following treatment for substance abuse; however, the role that drug attitude plays in the amount of time between treatment and relapse is not known. Research regarding the relationship between attitude and behavior change, drug use and relapse, gender differences in relapse, ways to measure drug attitude, and the relationship between drug attitude and drug use are discussed. The present study utilized a data set that consisted of one hundred subjects who participated in residential treatment for addiction. All subjects were dually diagnosed with major mental illness and a substance use or abuse disorder. The overall purpose of the present study was to examine the relationship between drug attitude at intake and time to relapse following completion of residential treatment. Results indicated that there was no significant relationship between drug attitude and time to relapse following treatment. Results further indicated that there were no differences in scores on Campbell's Drug Attitude Scale for males and females and no difference in time to relapse for males and females. Finally, results demonstrated that scores on the Attitude subscale and the Clinical subscale of Campbell's Drug Attitude Scale did not significantly predict time to relapse.