Expatriates are the representative of parent companies in overseas subsidiaries. Expatriates¡¦ stress would impact to both company and their personal life. To help multinational companies decrease work stress of expatriates and manage work stress problem, the objective of this research is to find personal characteristic factors affecting work stress of overseas expatriates in Thailand. The questionnaires were distributed to 120 respondents, valid samples are 105 persons. The finding shows that there is no significantly different in work stress between male and female expatriates, divorced respondents have work stress more than single and married group, elder expatriates more concern with stressors than younger expatriates, and stressor caused stressful to managers more than officers. ¡§Lack of training¡¨ and ¡§reward and compensation¡¨ are stressors respondents most concern. Therefore, supporting and training program are the things that expatriates expect from parent company. To decrease expatriates¡¦ work stress, company should provide pre and post departure program, language training program, and prepare suitable facilities to fit expatriates needs during their overseas assignments.