This thesis focuses on the design and implementation of an application involving the principles of DNA computing simulation for solving some selected problems. DNA computing represents an unconventional computing paradigm that is totally different from the concept of electronic computers. The main idea of DNA computing is to interpret the DNA as a medium for performing computation. Despite the fact, that DNA reactions are slower than operations performed on computers, they may provide some promising features in the future. The DNA operations are based on two important aspects: massive parallelism and principle of complementarity. There are many important problems for which there is no algorithm that would be able to solve the problem in a polynomial time using conventional computers. Therefore, the solutions of such problems are searched by exploring the entire state space. In this case the massive parallelism of the DNA operations becomes very important in order to reduce the complexity of finding a solution.

The aim of this theses is a sensitivity analysis of the tightness properties of the press-fit joined of the fuel pressure vessel Common Rail and the low pressure connector. Possible solutions were analyzed, where the fractional factorial design of a numerical experiment resolution four was chosen. Results of the thesis are statistically significant factors used in formulating the construction change recommendations.

The diploma is focused on optimizing of rating during the process of painting by means of experimental methods and statistic analysis. Description of the study of the present state of painting process, result analysis and the project of optimal pre-set in practice.

Aim of this work is to study the impact of inaccuracy in execution of required task (inaccuracy in subject’s behavioral response to experimental stimulation) by person who undergoes fMRI examination. The work is solved in several stages. First, theoretical analysis of inaccuracy in fMRI experiment was performed, and simulations with synthetic data were created. Several variables in general linear model and t-statistics were followed. We found that estimated effect size depends linearly on covariance between the corresponding columns of X and D matrices or their linear combination. The component of residual variance caused by inaccuracy is negligible at real-life noise levels. In such case, moreover, the dependence of t-statistics on inaccuracy becomes linear. Next, our theoretical results (dependencies/characteristics of variables) were verified using real data. All results were confirmed. Last, I focused on possible practical use of the uncovered characteristics and dependencies. Optimization of experimental design with respect to inaccuracy, correction of inaccurate results and reliability of inaccurate results are introduced and discussed. Especially, the calculation of maps of maximal tolerable inaccuracy can be useful to find robust or weak (tending to be not detected or to be significantly different from accurate value) activation in real fMRI experiments.

The use of information and communication technologies, including computer graphics, in teaching chemistry is one of the frequent issues of contemporary chemistry didactics. Current publications are mainly focused on displaying structure of chemical compounds and symbolic form of chemical reactions. This thesis offers a more complex view on the computer graphics and other means of information and communication technologies - their possibilities and limits of use in teaching. The goal of the thesis is to provide an overview of selected computer-graphics technologies and to discuss their role during current curricular reform, based on current problems identified by students attending chemistry-teacher training courses and chemistry teachers. Usability of selected elements in pre-teaching and teaching phases was checked. Innovations of contemporary teaching methods were proposed using computer graphics. The thesis is focused on the area of visualization of educational content with use of computer graphics, computer-assisted innovation of methods and educational content, computer games and the role of computer graphics in didactic transformation. Two textbooks for lower-secondary and upper-secondary schools were created. These textbooks contain newly developed parts using computer graphics. According to...

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Hamplová, K.; Transformations of roles and significations of object and material in a visual game. [Diploma thesis] Prague 2014 - Charles University, Faculty of education, 99 pages In my thesis I examine the process of transformation of roles and significations of object and material in visual games. I focus on the game as the experiment with characteristics of objects. I explore using objects and materials as the instruments for opening fictional worlds. A brief outline of the theories of perception of objects and their significations and theories of games and fictional worlds illustrates the base of the theme. Various views on the alterations of significations in creative process are illustrated with a selection of works of contemporary artists. In the didactic part I examine the characteristic position of the make-believe games in the development of a child and possible applications of those characteristics in art education. I also describe the design and realization of my didactic project dealing with this issue there. The applied part of my thesis is a natural extension and application of the thoughts delineated in the theoretic part. Powered by TCPDF (www.tcpdf.org)

This doctoral thesis concerns the designs, creation, and a pilot survey of real remotely controlled laboratories that can be used for the introduction to modern physics within the integrated e-learning strategy. With grant support four new remote laboratory experiments could be created, featuring some innovations like the possibility to modify experimental setup, and the design allowing to make a mistake and to obtain nonsensical experimental data in order to test students' critical thinking. The new remote experiment topics are: laws of radioactivity, polarisation state of light, photoelectric effect, and the origin of spectral lines. The emphasis is put on easy experimental data acquision (measurement, record, and download) for further scientific statistical or advanced graphical data proces- sing. The pilot survey aims to select adequate research designs, tools, and data sources and it describes the results and experience from the observation at several Czech secondary schools. The most interesting findings were revealed by action log file analysis and interviews with teachers and students. Finally, real usability of remote laboratory experiments in lessons and physics education is discussed. 1

The ATLAS experiment is one of the two general-purpose detectors at the Large Hadron Collider at CERN near Geneva. The goals of this particle physics experiment are the search for new physics phenomena and precision measurement of the particle interactions. Tilecal is the central hadronic calorimeter of the ATLAS. The calorimeter time calibration is important for the time-of-flight measurement of particles (used in some analyses) as well as for the actual energy reconstruction. 1

Im Rahmen dieser Arbeit erfolgte der Aufbau eines neuartigen Versuchsstandes zum praxisnahen Test von Wandaufbauten (VS-WA; Probendimension: 1,9 m x 1,9 m x 0,5 m). Mit dem VS sind praxisnahe Untersuchungen von Dämm- und Dichtstoffen sowie Wandsegmentmaterialien thermischer Energiespeicher in einer Einheit durchführbar. Aufgrund der drehbaren Lagerung des VS ist es möglich, vertikale (Wandbereich) und horizontale (Deckenbereich) Aufbauten zu untersuchen. Mit dem VS erfolgt eine experimentelle Bestimmung von effektiven Wärmeleitfähigkeiten zweier aussichtsreicher Wärmedämmstoffe (Polyurethan-Granulat und expandierte Polystyrol-Partikel). Die Untersuchungsergebnisse zeigen für den vertikalen Betrieb des VS eine erhöhte effektive Wärmeleitfähigkeit im Vergleich zu den Stoffwerten der Hersteller. Der Grund hierfür ist, basierend auf der Auswertung von Temperaturprofilen, ein signifikanter Anteil an freier Konvektion. Dies ist trotz niedriger Permeabilitäten der untersuchten Schüttgüter und demnach entgegen dem aktuellen Stand der Wissenschaft der Fall. Ohne den neuen VS mit den hier realisierten Maßen, wären diese Effekte nicht messbar gewesen (z. B. bei Untersuchungen mit Ein- oder Zwei-Platten-Apparaturen). Die Ergebnisse können dazu beitragen, erhöhte Wärmeverluste an realen Bauwerken zu erklären und zu vermeiden. / Within the context of this thesis, a new test rig for the practical testing of wall structures (VS-WA; sample size: 1.9 m x 1.9 m x 0.5 m) was set up. With the test rig, practical investigations of insulating and sealing materials as well as wall segment materials of thermal energy stores are possible in one unit. Since the test rig is pivoted it is also possible to examine vertical (wall area) and horizontal (ceiling area) structures. The present thesis deals with the experimental determination of the effective thermal conductivity of two promising thermal insulation materials (polyurethane granulate and expanded polystyrene particles). The test results show an increased effective thermal conductivity for the vertical orientation of the VS-WA compared to the material properties given by the manufacturers. The reason for this is, based on the evaluation of temperature profiles, a significant portion of free convection. This is the case despite low permeabilities of the bulk materials investigated and thus contrary to the current state of scientific knowledge. Without the new test rig with the dimensions realized here, the discovered effects could not have been observed (e.g. investigations with one- or two-plate apparatuses). The results can contribute to explain and avoid increased heat losses in real building structures.