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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Deleterious Synergistic Effects of Concurrent Magnetic Field and Superparamagnetic (Fe3O4) Nanoparticle Exposures on CHO-K1 Cell Line

Coker, Zachary 05 1900 (has links)
While many investigations have been performed to establish a better understanding of the effects that magnetic fields and nanoparticles have on cells, the fundamental mechanisms behind the interactions are still yet unknown, and investigations on concurrent exposure are quite limited in scope. This study was therefore established to investigate the biological impact of concurrent exposure to magnetic nanoparticles and extremely-low frequency magnetic fields using an in-vitro CHO-K1 cell line model, in an easily reproducible manner to establish grounds for further in-depth mechanistic, proteomic, and genomic studies. Cells were cultured and exposed to 10nm Fe3O4 nanoparticles, and DC or low frequency (0Hz, 50Hz, and 100Hz) 2.0mT magnetic fields produced by a Helmholtz coil pair. The cells were then observed under confocal fluorescence microscopy, and subject to MTT biological assay to determine the synergistic effects of these concurrent exposures. No effects were observed on cell morphology or microtubule network; however, cell viability was observed to decrease more drastically under the combined effects of magnetic field and nanoparticle exposures, as compared to independent exposures alone. It was concluded that no significant difference was observed between the types of magnetic fields, and their effects on the nanoparticle exposed cells, but quite clearly there are deleterious synergistic effects of these concurrent magnetic field and nanoparticle exposure conditions.
2

Nízkoúrovňová měření a vyhodnocení vlivu magnetických polí na lidský organismus, jeho chování a rozhodování / Measuring and Evaluating the Effects of Low-Level Magnetic Fields on Human Behavior and Decision-Making

Hanzelka, Michael January 2017 (has links)
Presents results of research in the field of low-level electromagnetic fields interacting with the higher organisms, in the frequency band from 0,01 to 30 Hz effect on the individual or social group. Provides a description of the methodology of measuring and evaluating the impact of workplace assembled measuring low-level electromagnetic fields, extremely low frequency (ELF) on a sample of respondents. It was proposed measuring device for monitoring and evaluating how respondents' reactions to changes in the geomagnetic or external - external magnetic / electromagnetic field and to work for the measurement and evaluation of changes in external magnetic fields very low levels (ELF). This work is designed to process and evaluate implemented within experimental research into the influence of low-level magnetic fields in the Earth's resonator psychophysiological parameters of human organism and its behavior and decision-making. The work confirmed the influence of low-level magnetic fields on the psychophysiological parameters of the organism to be simultaneously confirmed the hypothesis established in accordance with the objectives of work.

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