This study examined the perceptions and behaviors of clergy and faith-based social service practitioners within the African-American faith community, in relationship to HIV/AIDS education and prevention. This study employed a descriptive exploratory design, utilizing quantitative and qualitative methods to analyze the secured data. The independent variables were clergy and faith-based social service practitioners. The three dependent variables were identified as perceptions (composed of health beliefs, attitudes, subjective norm and perceived behavioral control), intended behavior and actual behavior regarding HIV/AIDS education and prevention. Findings revealed a lack of significant difference in the perceptions of clergy and church workers regarding HIV/ AIDS education and prevention. However, there was a statistically significant difference in their intended and actual behaviors to provide HIV/AIDS information to various age groups in the church community.