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181	Análise do catabolismo da hemoglobina de Plasmodium falciparum. / Analysis of the haemoglobin catabolism of Plasmodium falciparum. Lindner, Jasmin 07 June 2017 (has links) O metabolismo de nutrientes abriga um alto potencial para o desenvolvimento de novos alvos quimioterápicos para o tratamento do parasita da malária Plasmodium falciparum. A partir de ensaios de crescimento do parasita dentro de eritrócitos geneticamente diferentes, concentrando-se na via catabólica da hemoglobina plasmodial usando parasitas transgênicos, a natureza protetora das variantes da hemoglobina foi investigada. Sendo que Falcipain 2 (FP2) prolifera três vezes mais elevada no sangue de células falciformes do que o Mock, a célula de controle. Adicionalmente, estudos de inibidores indicam que FP2 é uma proteína essencial para o parasita. Em cooperação com o DESY em Hamburgo, Alemanha a estrutura cristalina da amino peptidase P foi resolvida difratando até 1,7 Å. / The metabolism of nutrients harbors a high potential for the development of new chemotherapeutic targets for the treatment of the malaria parasite Plasmodium falciparum. From parasite growth assays within genetically different erythrocytes, concentrating on the catabolic pathway of plasmodial hemoglobin using transgenic parasites, the protective nature of hemoglobin variants was investigated. Since Falcipain 2 (FP2) proliferates three times higher in sickle cell blood than the Mock, the control cell. In addition, inhibitor studies indicate that FP2 is an essential protein for the parasite. In cooperation with DESY in Hamburg, Germany the crystalline structure of the amino peptidase P was resolved diffracting up to 1.7 Å. Plasmodium falciparum Plasmodium falciparum Anemia falciforme haemoglobin Hemoglobina protease Protease sickle cell trait
182	Drug resistance in Plasmodium falciparum : the role of point mutations in dihydropteroate synthase and dihydrofolate reductase analyzed in a yeast model / Hankins, Eleanor Gray. January 2001 (has links) Thesis (Ph. D.)--University of Washington, 2001. / Vita. Includes bibliographical references (leaves 92-99).
183	Heparan sulfate dependent sequestration during Plasmodium falciparum malaria / Vogt, Anna, January 2004 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 4 uppsatser.
184	Malaria on islands : human and parasite diversities and implications for malaria control in Vanuatu / Kaneko, Akira, January 1900 (has links) Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 7 uppsatser.
185	Variable surface molecules of the Plasmodium falciparum infected erythrocyte and merozoite / Haeggström, Malin, January 2006 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 4 uppsatser.
186	Ultrastructural studies of Plasmodium falciparum in human organs : the interactions between the parasitized erythrocytes and the host cells / Emsri Pongponrat, Sornchai Looareesuwan, January 2000 (has links) (PDF) Thesis (Ph.D. (Tropical Medicine))--Mahidol University, 2000.
187	Therapeutic response of falciparum malaria in relation to in vitro sensitivity of plasmodium falciparum / Buthsaraporn Surakhaka, Polrat Wilairatana, January 2000 (has links) (PDF) Thesis (M.Sc. (Tropical Medicine))--Mahidol University, 2000.
188	Clinical manifestation and treatment of non-severe falciparum malaria in Thai children / Suprotik, Ghagra, Chukiat Sirivichayakul, January 2004 (has links) (PDF) Thesis (M.C.T.M. (Tropical Pediatrics))--Mahidol University, 2004.
189	Clinical manifestation of uncomplicated falciparum malaria and vivax malaria in Thai children / Huot, Chantheany, Pornthep Chanthavanich, January 2004 (has links) (PDF) Thesis (M.C.T.M. (Tropical Pediatrics))--Mahidol University, 2004.
190	Identification of putative Plasmodium falciparum mefloquine resistance genes / Jeffress, Mara L., January 2004 (has links) Thesis (Ph. D.)--University of Washington, 2004. / Vita. Includes bibliographical references (leaves 135-171).

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