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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
31

Purification and characterisation of plasmodium falciparum Hypoxanthine phosphoribosyltransferase

Murungi, Edwin Kimathi. January 2007 (has links)
Malaria remains the most important parasitic disease worldwide. It is estimated that over 500 million infections and more that 2.7 million deaths arising from malaria occur each year. Most (90%) of the infections occur in Africa with the most affected groups being children of less than five years of age and women. this dire situation is exacerbated by the emrggence of drug resistant strains of Plasmodium falciparum. The work reported in this thesis focuses on improving the purification of PfHPRT by investigating the characteristics of anion exchange DE-52 chromatography (the first stage of purification), developing an HPLC gel filtration method for examining the quaternary structure of the protein and possible end stage purification, and initialcrystalization trials. a homology model of the open, unligaded PfHPRT is constructed using the atoomic structures of human, T.ccruz and STryphimurium HPRT as templates. / Magister Scientiae - MSc
32

Antibody responses in Plasmodium falciparum malaria and their relation to protection against the disease /

Bolad, Ahmed Kamal, January 2004 (has links)
Diss. (sammanfattning) Stockholm : Univ., 2004. / Härtill 4 uppsatser.
33

Diversity and dynamics of Plasmodium falciparum malaria /

Färnert, Anna, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 6 uppsatser.
34

Gene expression profiling of polyamine-depleted Plasmodium falciparum

Dhoogra, Minishca.. January 2007 (has links)
Thesis (M.Sc.)(Biochemistry))-University of Pretoria, 2007. / Summary in English. Includes bibliographical references. Available on the Internet via the World Wide Web.
35

Focused chemical libraries targeting pyrimidine metabolism in Plasmodium falciparum /

Farajallah, Azizeh M. January 2007 (has links)
Thesis (Ph. D.)--University of Washington, 2007. / Vita. Includes bibliographical references (leaves 199-212).
36

Lipoic acid protein ligases in Plasmodium spp. /

Günther, Svenja. January 2008 (has links)
Thesis (Ph.D.) - University of Glasgow, 2008. / Ph.D. thesis submitted to the Division of Infection and Immunity, Institute of Biomedical and Life Sciences, University of Glasgow, 2008. Includes bibliographical references. Print version also available.
37

Pharmacological effect of MEK inhibitors on plasmodium falciparum

Sicard, Audrey. January 2008 (has links)
Thesis (MSc.) - University of Glasgow, 2007. / MSc. thesis submitted to the Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, 2008. Includes bibliographical references. Print copy also available.
38

A genetic analysis to elucidate the function of the Plasmodium falciparum parasitophorous vacuole protein, PfPV1

Chu, Trang T. T. Unknown Date (has links)
Univ., Diss., 2009--Marburg. / Zsfassung in dt. Sprache.
39

Discovery and characterization of polyamine analogues as inhibitors of the Plasmodium falciparum polyamine pathway using cheminformatics

De Bruin, Jurgens Jacobus.. January 2009 (has links)
Thesis (M.Sc.)(Biochemistry))--University of Pretoria, 2008. / Includes summary.
40

Functional characterisation of aquaporins from Plasmodium falciparum, Toxoplasma gondii und Trypanosoma brucei

Pavlovic-Djuranovic, Slavica, January 2006 (has links)
Tübingen, Univ., Diss., 2006.

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