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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Sulfamethazine in food : a new approach to screeningHancox, Jill Nicola January 1998 (has links)
The aim of the research was to use the principles of immunoassays and fluorescence spectroscopy to detect the presence of 4-amino-N-(4,5- dimethyl-2-pyrimidinyl)benzenesulfonamide, commonly known as sulfamethazine, in food.
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Improvement of a fluorescence immunoassay with a compact diode-pumped solid state laser at 315 nmNiederkrüger, Matthias, Salb, Christian, Beck, Michael, Hildebrandt, Niko, Löhmannsröben, Hans-Gerd, Marowsky, Gerd January 2006 (has links)
We demonstrate the improvement of fluorescence immunoassay (FIA) diagnostics in deploying a newly developed compact diode-pumped solid state (DPSS) laser with emission at 315 nm. The laser is based on the quasi-three-level transition in Nd:YAG at 946 nm. The pulsed operation is either realized by an active Q-switch using an electro-optical device or by introduction of a Cr<SUP>4+</SUP>:YAG saturable absorber as passive Q-switch element. By extra-cavity second harmonic generation in different nonlinear crystal media we obtained blue light at 473 nm. Subsequent mixing of the fundamental and the second harmonic in a β-barium-borate crystal provided pulsed emission at 315 nm with up to 20 μJ maximum pulse energy and 17 ns pulse duration. Substitution of a nitrogen laser in a FIA diagnostics system by the DPSS laser succeeded in considerable improvement of the detection limit. Despite significantly lower pulse energies (7 μJ DPSS laser versus 150 μJ nitrogen laser), in preliminary investigations the limit of detection was reduced by a factor of three for a typical FIA.
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