This study concludes two parts. In the first part, we establish the model of the interaction between two cell populations following the concept of the random-walk, and assume the cell movement is constrained by space limitation primarily. In the other part, the interaction model is deduced from the concept of the flux motion, and the movement is constrained by space limitation, too. Furthermore, we analyze two models to obtain the behavior of two cell populations as time is close to the initial state and far into the future. / This study concludes two parts. In the first part, we establish the model of the interaction between two cell populations following the concept of the random-walk, and assume the cell movement is constrained by space limitation primarily. In the other part, the interaction model is deduced from the concept of the flux motion, and the movement is constrained by space limitation, too. Furthermore, we analyze two models to obtain the behavior of two cell populations as time is close to the initial state and far into the future.