Growth of Corbicula fluminea was monitored in the laboratory. Three experiments were conducted. Experiment I utilized three substrates and one food type. Experiment II utilized three substrates and two food types. Experiments I and II were conducted to determine if substrate type or food type effected growth. Experiment III used no substrates, one food type and was conducted to determine growth response to different types of water. Clams were maintained in three substrates: sand, gravel and clay. Clams were also maintained without substrate. Growth was monitored by measuring shell length (mm) and recording the weight (mg) of clams over a period of thirty days. At the end of the test period data were evaluated for normality and homogeneity.