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Non-invasive assessment of gastrointestinal function using breath test technology : investigations in health and disease.Symonds, Erin Leigh January 2002 (has links)
Title page, table of contents and abstract only. The complete thesis in print form is available from the University of Adelaide Library. / Assessment of gastric emptying in animals is hampered by the lack of a technique that is noninvasive and does not involve sacrificing the animal. The primary aims of these studies therefore were to develop the breath test for the mouse and then investigate gastric emptying rates in physiological, pathological and pharmacological studies. After an overnight fast, mice were fed a solid or liquid meal that contained a ¹³C-labelled substrate, and placed in breath collection chambers. Breath samples collected at intervals were analysed for levels of ¹³C0₂, with the rate of appearance in the breath giving a measure of the gastric emptying rate. The breath testing technique was shown to be reproducible and sensitive enough to be able to detect induced alterations to gastric emptying, with results comparable to those obtained from other techniques. The breath test was used to assess gastric emptying in mice and showed that: (1) H. pylori infection accelerated gastric emptying in the initial weeks of infection, whilst a more severe stomach inflammation caused dysmotility; (2) baclofen (a potential reflux therapy) accelerated gastric emptying of solids and delayed liquid emptying in a dosedependent manner; and (3) mice with a high daily food intake had faster emptying compared to those with low intake, which resulted in the same weight gain of the two groups. Breath testing was also used in adults and children and showed that: (1) increasing the caloric content of a solid meal delayed the emptying of the solid, but not of a liquid given simultaneously; (2) gastric emptying rate is correlated to the amount of colonic gas produced; and (3) improvement in pancreatic lipase activity with pancreatic enzyme replacement is inversely related to the gastric emptying time. Breath testing was also used to show that substrates with a natural ¹³C-enrichment can be used to assess small intestinal enzyme activity. Breath testing is a sensitive and reproducible tool to investigate gastric emptying in mice. Its noninvasive nature allows it to be repeated within each subject which is useful for follow-up investigations. It can now be applied further to a range of disease, pharmacological and nutritional investigations. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1082934 / Thesis (Ph.D.) -- University of Adelaide, Dept. of Physiology, 2002
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Non-invasive assessment of gastrointestinal function using breath test technology : investigations in health and disease.Symonds, Erin Leigh January 2002 (has links)
Title page, table of contents and abstract only. The complete thesis in print form is available from the University of Adelaide Library. / Assessment of gastric emptying in animals is hampered by the lack of a technique that is noninvasive and does not involve sacrificing the animal. The primary aims of these studies therefore were to develop the breath test for the mouse and then investigate gastric emptying rates in physiological, pathological and pharmacological studies. After an overnight fast, mice were fed a solid or liquid meal that contained a ¹³C-labelled substrate, and placed in breath collection chambers. Breath samples collected at intervals were analysed for levels of ¹³C0₂, with the rate of appearance in the breath giving a measure of the gastric emptying rate. The breath testing technique was shown to be reproducible and sensitive enough to be able to detect induced alterations to gastric emptying, with results comparable to those obtained from other techniques. The breath test was used to assess gastric emptying in mice and showed that: (1) H. pylori infection accelerated gastric emptying in the initial weeks of infection, whilst a more severe stomach inflammation caused dysmotility; (2) baclofen (a potential reflux therapy) accelerated gastric emptying of solids and delayed liquid emptying in a dosedependent manner; and (3) mice with a high daily food intake had faster emptying compared to those with low intake, which resulted in the same weight gain of the two groups. Breath testing was also used in adults and children and showed that: (1) increasing the caloric content of a solid meal delayed the emptying of the solid, but not of a liquid given simultaneously; (2) gastric emptying rate is correlated to the amount of colonic gas produced; and (3) improvement in pancreatic lipase activity with pancreatic enzyme replacement is inversely related to the gastric emptying time. Breath testing was also used to show that substrates with a natural ¹³C-enrichment can be used to assess small intestinal enzyme activity. Breath testing is a sensitive and reproducible tool to investigate gastric emptying in mice. Its noninvasive nature allows it to be repeated within each subject which is useful for follow-up investigations. It can now be applied further to a range of disease, pharmacological and nutritional investigations. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1082934 / Thesis (Ph.D.) -- University of Adelaide, Dept. of Physiology, 2002
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Non-invasive assessment of gastrointestinal function using breath test technology : investigations in health and disease.Symonds, Erin Leigh January 2002 (has links)
Title page, table of contents and abstract only. The complete thesis in print form is available from the University of Adelaide Library. / Assessment of gastric emptying in animals is hampered by the lack of a technique that is noninvasive and does not involve sacrificing the animal. The primary aims of these studies therefore were to develop the breath test for the mouse and then investigate gastric emptying rates in physiological, pathological and pharmacological studies. After an overnight fast, mice were fed a solid or liquid meal that contained a ¹³C-labelled substrate, and placed in breath collection chambers. Breath samples collected at intervals were analysed for levels of ¹³C0₂, with the rate of appearance in the breath giving a measure of the gastric emptying rate. The breath testing technique was shown to be reproducible and sensitive enough to be able to detect induced alterations to gastric emptying, with results comparable to those obtained from other techniques. The breath test was used to assess gastric emptying in mice and showed that: (1) H. pylori infection accelerated gastric emptying in the initial weeks of infection, whilst a more severe stomach inflammation caused dysmotility; (2) baclofen (a potential reflux therapy) accelerated gastric emptying of solids and delayed liquid emptying in a dosedependent manner; and (3) mice with a high daily food intake had faster emptying compared to those with low intake, which resulted in the same weight gain of the two groups. Breath testing was also used in adults and children and showed that: (1) increasing the caloric content of a solid meal delayed the emptying of the solid, but not of a liquid given simultaneously; (2) gastric emptying rate is correlated to the amount of colonic gas produced; and (3) improvement in pancreatic lipase activity with pancreatic enzyme replacement is inversely related to the gastric emptying time. Breath testing was also used to show that substrates with a natural ¹³C-enrichment can be used to assess small intestinal enzyme activity. Breath testing is a sensitive and reproducible tool to investigate gastric emptying in mice. Its noninvasive nature allows it to be repeated within each subject which is useful for follow-up investigations. It can now be applied further to a range of disease, pharmacological and nutritional investigations. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1082934 / Thesis (Ph.D.) -- University of Adelaide, Dept. of Physiology, 2002
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Characterising the Biophysical Properties of a Mangrove Forest to Inform Mosquito ControlJonathan Mark Knight Unknown Date (has links)
No description available.
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Advanced food product quality planning using integrated quantitative techniquesPable, Anant. January 2007 (has links)
Thesis (M.S.)--State University of New York at Binghamton, Dept. of Systems Science and Industrial Engineering, 2007. / Includes bibliographical references.
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Separating maps between function spacesCheong, Chi-weng, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaf 45-46) Also available in print.
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The Shields-Harary number of graphsHolliday, John Edwin, Johnson, Peter D. January 2004 (has links) (PDF)
Dissertation (Ph.D.)--Auburn University, 2004. / Abstract. Vita. Includes bibliographic references.
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Algebras of analytic functions on plane setsDavie, A. M. January 1970 (has links)
Originally issued as the author's thesis, Dundee University. / Cover title. Bibliography: leaves [92-96].
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Gastrointestinal microecology of Balb/C nude miceBrown, James F. January 1977 (has links)
Thesis (M.S.)--Wisconsin. / Includes bibliographical references (leaves 42-44).
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Relative korovkin approximation in function spaces /Ng, Ka-lok. January 1995 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1996. / Includes bibliographical references (leaf 57-59).
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