Life-Cycle Assessment (LCA) is an analytic method for evaluation of environmental impacts of products, services and technologies. It is associated with all the stages of a product's life. The environmental impacts are evaluated on the basis of material and energetic flows, which are in influence with the environment. These impacts are always determined in the relation with the function of the product or the service and so it is possible to compare them with the other alternatives. One of the most important reasons why I have chosen this dissertation thesis subject was the growing public interest in impacts of the building constructions on the environment and human organism. Only a few experts and scientific research centres deal with the problem of environmental impacts of the buildings in the Czech Republic so the main goal of this thesis is to help with a spreading a knowledge about it. There are four main problems to solve in the thesis: determination of environmental impacts of selected materials which are missing in available databases, creation of life cycle models of evaluated buildings, determining the most appropriate functional unit and determining the contents of the recommended LCA protocol for building analysis. In the first phase of the thesis there was built a detailed life cycle model of the reference building on the basis of available documents and databases. This "cradle to cradle" LCA model was then optimized for a large number of life cycle scenarios to determine the significance of the impact of individual variables on the overall environmental impact of the building. The knowledge gained from this analysis was applied to the lifecycle models of other buildings and then there was assembled the recommended form of the LCA protocol. In the final stage, the results of the environmental impacts were quantified on the different functional units which were used for determining the appropriate form.

The topic of the master thesis is new medico-social facility hospice St. Michaela. The purpose of the object is the maximizing of improvement in the quality of life of dying, severely ill and incurable patients, with the use of palliative care. The construction follows the Complex of Regional Hospital Náchod. Together with as a retirement home Náchod completes a support network of health and social care. The building is designed as a four-building storey and is partially embedded into the sloping terrain. Floors are divided into individual facilities and together constitute a functional unit. In the basement is the technical room, warehouses, garages and kitchen facilities. On the ground floor are then socio-public rooms and facilities. On the second floor is located hedmaster of hospice and accommodation area. The third floor is devoted to the accommodation area. The proposed structure made of brick longitudinal system, supplemented by concrete basement walls. The horizontal structure is made of filigree ceiling panels. Stairs are designed as a precast concrete and steel. Individual roof structures is made from unwalkable, walkable and vegetation compositions. The cladding consists of ventilated facade of glass and wooden panels. Foundations are designed from the lineal foundation.