No description available.

Thesis (M.S.)--Brandeis University, 2009. / Title from PDF title page (viewed on May 29, 2009). Includes bibliographical references.

Thesis (M.S.)--Brandeis University, 2009. / Title from PDF title page (viewed on May 29, 2009). Includes bibliographical references.

Adult Polycystic Kidney Disease (APKD) is a genetic disease transmitted in an autosomal dominant fashion. There is no cure. Treatment is of the symptoms as they appear usually in adulthood. Patients affected by APKD may receive genetic counselling from renal physicians. The aims of genetic counselling can be described through paradigms which reflect the current understanding of genetics and knowledge of the illnesses. The availability of new diagnostic techniques creates a new paradigm concerned with the ethical issues of genetic testing and counselling. An investigation into patients' knowledge, perceptions and understanding of genetic counselling was undertaken at the Renal Unit of Glasgow Royal Infirmary, prior to the establishment of a screening and counselling service for those at risk for APKD. The main findings of the study were: the majority of patients had received some genetic counselling from renal physicians; the majority of patients had relatively good knowledge of the symptoms of and treatments for APKD; nevertheless patients believed that the two most important items to be included in genetic counselling were information about the symptoms and the treatment of APKD; patients did not fully understand the genetic inheritance of APKD; they described the risk of transmission of APKD (50-50) as a medium risk; almost all patients recommended that their at risk relatives and their children be tested for APKD; prior to the availability of prenatal diagnosis, patients thought that their children should be tested between the ages of 16 and 20. A secondary study, including spouses of those with APKD and also haemophiliacs and their spouses, found that respondents favoured prenatal testing without termination of pregnancy and that both diseases were rated as being of medium severity. These findings raise ethical issues for those giving genetic counselling, and have implications for the content of genetic counselling.

No description available.

Genetic counseling for women with advanced maternal age is well established medical standard of care. However, only one study has yet been done to test the validity of that policy. Records of 283 patients referred for genetic counseling with advanced maternal age as a primary indication were examined. Of these, 57.6% had at least one additional indication. This value did differ significantly from Rubin's data which reported a 43.3% rate (X2 = 13.01, p > 0.001). The additional indications were broken down according to McKusick's system, and a statistical difference between my and Rubin's data was found in the autosomal dominant, autosomal recessive, potential teratogenic exposure and miscellaneous categories. There was no significant statistical difference between my and Rubin's data in the X-linked, chromosomal anomalies and multifactorial groups. These data underscore the need for physicians to refer patients with advanced maternal age for genetic counseling, and provides a scientific basis for doing so.

Thesis (M.A.)-- Sarah Lawrence College, 2005. / Includes bibliographical references. Also available on the Internet.

Thesis MHSc(GenetCouns)--University of Melbourne, Murdoch's Children's Research Institute and Dept. of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, 2010. / Typescript. By Thesis only. Includes bibliographical references (p. 104-117)

Thesis--University of Oklahoma. / Bibliography: leaves 48-51.

No description available.