Taiwan¡¦s high-tech multinational corporations have two main brand strategies. One is OEM/ODM, and other one is OBM. Different brand strategy will influence the consideration of global arrangement governing the organization network and the global knowledge transfer model. There are five roles building in different meaning in global organization network. And in the knowledge transfer model, there are three different dimensions named knowledge transfer fountain-heading, knowledge transfer interface and knowledge accumulate meaning. According to the administrative department of Hsinchu Science-Based Industrial Park¡¦s meeting for defining the classification of high-tech industries. This research chose four multinational corporations which nationality is Taiwan. These are the computer-related manufacturing industries and the communication-related manufacturing industries. This research concludes some propositions through the interview with top managers of these sample corporations. Positions are as follows: Proposition 1: Different brand strategies will influence the classification of tendency in exploiting advance technology. Proposition 2: Headquarter will play the different roles in global research network according to the different brand strategy. Proposition 3: The subsidiaries of high-tech corporations will have diversity of role playing and different frequency of knowledge transferring according to brand strategies. Proposition 4: The brand strategies will influence types and frequency of knowledge transferring. Proposition 5: Brand strategies will influence the market knowledge¡¦s flowing direction. Proposition 6: In technology knowledge transfer, the low-end and manufacturing skill will duplicate to the manufacture-based plant, and the high-level and advance knowledge will keep in the headquarter. Proposition 7: human being is the most important interface in the knowledge transfer process.