When examining the world population, approximately 11% of people experience migraines. A chronic migraine is classified as a headache that occurs on a frequent basis in which the pain is quick to occur unilaterally, and is a throb that is considered a moderate to intense level of pain. It is believed that a migraine brain is intensely sensitive to deviations from homeostasis. This case series research investigated the effect of a glutenree diet on individuals with chronic migraines. Participants completed a five-month study consisting of dietary and physical measurements, recording migraines, and a glutenree diet with a re-introduction period. In conclusion, the results were difficult to determine due to various limitations. This study appeared to have the most effect on one participant by reducing his migraines from 10 to 3 per month. More research is necessary to determine the efficacy of a glutenree diet to help alleviate migraines.