<p dir="ltr">This dissertation presents the findings and research conducted during my Ph.D. study, which focuses on developing grasp policies for modular end-effectors on mobile manipulation platforms operating in cluttered environments. The primary objective of this research is to enhance the performance and accuracy of robotic manipulation systems in complex, real-world scenarios. The work has potential implications for various domains, including the rapidly growing Industry 4.0 and the advancement of autonomous systems in space habitats.</p><p dir="ltr">The dissertation offers a comprehensive literature review, emphasizing the challenges faced by mobile manipulation platforms in cluttered environments and the state-of-the-art techniques for grasping and manipulation. It showcases the development and evaluation of a Modular End-Effector System (MEES) for mobile manipulation platforms, which includes the investigation of object 6D pose estimation techniques, the generation of a deep learning-based grasping dataset for MEES, the development of a suction cup gripper grasping policy (Sim-Suction), the development of a two-finger grasping policy (Sim-Grasp), and the integration of Modular End-Effector System grasping policy (Sim-MEES). The proposed methodology integrates hardware designs, control algorithms, data-driven methods, and large language models to facilitate adaptive grasping strategies that consider the unique constraints and requirements of cluttered environments.</p><p dir="ltr">Furthermore, the dissertation discusses future research directions, such as further investigating the Modular End-Effector System grasping policy. This Ph.D. study aims to contribute to the advancement of robotic manipulation technology, ultimately enabling more versatile and robust mobile manipulation platforms capable of effectively interacting with complex environments.</p>