Functional recovery of the upper limb after stroke is influenced by many factors, one being amount of affected arm and hand use following stroke. In the healthy population, amount of hand use is influenced by degree of hand dominance. Depending on side of stroke and previous hand dominance, these preferences may be altered, consequently affecting the amount of upper limb use. Determining hand preference in patients after stroke, when measured, is commonly assessed with questionnaires; however, these reports are subjective and patients may have difficulty recalling from memory which hand they use for the numerous activities on the questionnaire. A preferential reaching task has been shown to correlate with the degree of hand dominance as determined by the Waterloo Handedness Questionnaire, providing an objective performance-based method to assess the continuum of hand dominance in healthy subjects. A modified version of this preferential reaching task, with varying degrees of proximal to distal control, was used to investigate the influence of impairment, pre-stroke dominance and task difficulty on affected arm reach percentage. Results of the study revealed that it is feasible to administer a modified preferential reaching task in the stroke population, as the test could be completed in less than 10 minutes with no adverse effects reported from the patients. Heterogeneity made it difficult to detect statistical effects of task difficulty and pre-stroke dominance on post-stroke preference; however, there were trends observed indicating that patients with their dominant arm affected may have greater preference for the affected arm compared to those with their non-dominant arm affected. This was despite similar impairment levels between these patient groups. Preference for the dominant arm (whether affected or unaffected) was stronger when the task was at midline or in contralateral space, and when tasks required the greatest degree of distal control. In future, the degree of hand preference measured with this tool will have important implications for identifying areas in therapy requiring greater focus as well as identifying individuals who would most benefit from therapies that promote affected arm use, such as constraint induced movement therapy

Functional recovery of the upper limb after stroke is influenced by many factors, one being amount of affected arm and hand use following stroke. In the healthy population, amount of hand use is influenced by degree of hand dominance. Depending on side of stroke and previous hand dominance, these preferences may be altered, consequently affecting the amount of upper limb use. Determining hand preference in patients after stroke, when measured, is commonly assessed with questionnaires; however, these reports are subjective and patients may have difficulty recalling from memory which hand they use for the numerous activities on the questionnaire. A preferential reaching task has been shown to correlate with the degree of hand dominance as determined by the Waterloo Handedness Questionnaire, providing an objective performance-based method to assess the continuum of hand dominance in healthy subjects. A modified version of this preferential reaching task, with varying degrees of proximal to distal control, was used to investigate the influence of impairment, pre-stroke dominance and task difficulty on affected arm reach percentage. Results of the study revealed that it is feasible to administer a modified preferential reaching task in the stroke population, as the test could be completed in less than 10 minutes with no adverse effects reported from the patients. Heterogeneity made it difficult to detect statistical effects of task difficulty and pre-stroke dominance on post-stroke preference; however, there were trends observed indicating that patients with their dominant arm affected may have greater preference for the affected arm compared to those with their non-dominant arm affected. This was despite similar impairment levels between these patient groups. Preference for the dominant arm (whether affected or unaffected) was stronger when the task was at midline or in contralateral space, and when tasks required the greatest degree of distal control. In future, the degree of hand preference measured with this tool will have important implications for identifying areas in therapy requiring greater focus as well as identifying individuals who would most benefit from therapies that promote affected arm use, such as constraint induced movement therapy

Lateral biases are evident in a number of behaviors across many organisms. The present work was concerned with the particular lateral phenomenon known as handedness. Previous research has suggested that handedness is not a one-dimensional trait. This study evaluated handedness using two factors: hand preference and hand performance. Hand preference refers to the hand chosen to carry out a given action whereas hand performance refers to each hand’s ability, or skill, at carrying out that action. The relationship between hand preference and hand performance has been studied extensively in adults, but the larger body of work with human infants has only assessed hand preference. The goals of this study were to develop a methodology to measure infant hand performance and to begin to examine the relationship between hand preference and hand performance in development. To this end, thirty-six 11-month-old infants were videotaped completing three tasks. The first task assessed hand preference and consisted of a free-play period during which infants were presented with a series of toys that afforded different types of manipulation. The second and third tasks were novel measures of infant hand performance. The second task assessed the infant’s gross motor skills and involved fitting a ball into the top aperture of a toy. The third task assessed the infant’s fine motor skills by requiring infants to retrieve a Cheerio from a stationary plastic cup. Overall, the majority of infants were found to be right-preferent. This was in agreement with previous studies of hand preference in 11-month-olds as well as the pattern of hand preference seen in adults. There was no group-level asymmetry on either measure of hand performance. Hand preference was regressed on hand performance in an overall model of handedness. The right hand’s performance on each task significantly predicted hand preference scores. This was the first study to demonstrate that hand preference can be predicted by hand performance in infants. Future work will examine infant hand proficiency in greater detail as well as the relationship between hand preference and hand performance in nonhuman primate infants.

The database on hand preferences in non-human primates provides inconsistent and inconclusive findings, and is plagued by gaps and methodological issues. I studied hand preferences in the bonobo, which is a very interesting model for investigating evolutionary hypotheses on human handedness. There are few previous data on bonobos and they are from small samples and for relatively simple tasks. I studied a large sample of 94 bonobos in three zoos and one sanctuary, on a variety of actions. Five studies were performed to record: 1. hand use for spontaneous daily actions (non-social). 2. hand use for the tube task , a task that requires a manipulative bimanual coordinated precise action. 3. hand use for using a stick as a probe ( termite fishing ). 4. hand use for spontaneous social actions and gestures, recorded during their social interactions (intra-specific) and during interactions with humans (inter-specific). 5. hand use for induced begging gestures (begging for food from the observer). The results show significant manual laterality in almost all the behaviours studied. The hand preferences were present on an individual basis. The numbers of right-handed and left-handed individuals were similar, indicating no group-level bias, for any of the actions studied. There was no significant effect of the settings, rearing history, sex and age (except in study 2 where adults were more right-handed than younger subjects). I examined different factors that have been proposed as selective pressures for the emergence of handedness. Laterality was influenced by: postural demands (posture, activity of the other hand), precision, grip type, manipulation or bimanual coordination, tool-use, throwing, communication. Notably, the laterality was very marked for the tube task , the termite fishing task and the begging experiment, which suggests that the factors involved in these tasks could be important factors regarding laterality.

<p>The aim of the present study was to determine the distributions of and correlations between hand preference, visual acuity and eye preference through a series of tests in 50 males 50 females aged between 17 and 39 years. Handedness was determined through the Edinburgh handedness inventory questionnaire. The handedness distribution was: right-handed 90%, left-handed 1 %, and ambidextrous 9%. I found that 30 % had better visual acuity with their right eye, 39 % had better visual acuity with their left eye, and 31% had the same visual acuity with both eyes. 75.2% on average used their right eye in the battery of tests and 24.8% on average used their left eye. There were no statistically significant differences between the sexes or age groups with any of the measures. No correlation was found between eye preference and visual acuity or eye preference and hand preference among all subjects. No statistically significance between the sexes was found.</p>

The aim of the present study was to determine the distributions of and correlations between hand preference, visual acuity and eye preference through a series of tests in 50 males 50 females aged between 17 and 39 years. Handedness was determined through the Edinburgh handedness inventory questionnaire. The handedness distribution was: right-handed 90%, left-handed 1 %, and ambidextrous 9%. I found that 30 % had better visual acuity with their right eye, 39 % had better visual acuity with their left eye, and 31% had the same visual acuity with both eyes. 75.2% on average used their right eye in the battery of tests and 24.8% on average used their left eye. There were no statistically significant differences between the sexes or age groups with any of the measures. No correlation was found between eye preference and visual acuity or eye preference and hand preference among all subjects. No statistically significance between the sexes was found.

This dissertation presents three experiments to investigate the general distribution of hand preference across a reachable working space, as well as the effect of sensory information about the reaching hand, and if this distribution is affected by long term practice. In addition, the underlying mechanisms of hand preference behavior were investigated with the obtained kinematic data. Experiment 1 explored the distribution of hand preferences across the workspace among non-athlete right-handed participants, as well as the role that visual feedback might play in this distribution. Experiment 2 tested the hypothesis, if occlusion of visual feedback influences hand preference, accordingly interlimb differences. The third final experiment examined the effect of long term practice on hand preference among right-handed elite fencers. The first study showed that the choice of arms is related to the energetic cost and dynamic efficiency of the movements. The results of the second experiment displayed that the choice of hands changes under no visual feedback condition, demonstrating that the choice is active and not habitual, depending on sensorimotor performance asymmetries. The final experiment demonstrated that elite athletes have different patterns of limb selection than non- athletes. Athletes, specifically fencers, show improved coordination in their non-dominant arms, which apparently increases the selection of this arm for reaching. Overall, it was concluded that hand preference depends on sensorimotor performance asymmetries and influenced by the long term practice.

The present study addresses some of the problems in human handedness studies by noting the manual choices of one hundred twenty elementary pupils in the first through fifth grades. It discusses the value of the Van Riper critical angle board, the correlation indices of handedness based upon different types of activities, and the divergence with respect to degree and pattern of hand preference in the children.

This work examines the effect of participants' gender and handedness on the perception of short intervals of time. The time estimation task consisted of an empty production procedure with forty trials at each of four intervals of one, three, seven, and twenty seconds. The four target intervals represent a natural logarithmic progression and a series that bracket important temporal thresholds. The order of presentation of those intervals was randomized across participants but yoked across the sexes in each of the respective dominant hand groups. The two between-subject factors, with two levels each, were sex and handedness. Participants produced forty estimates at each of the required intervals, which was the first within-subject factor, estimated interval being the other. T-tests were conducted on the dependent measures, the time estimates in terms of their variability and their central tendency with respect to the target duration. If handedness plays a significant role in timing, this may indicate differences between hemispheric functioning as a possible causal mechanism. If there is cerebral asymmetry in time perception, namely if one hemisphere is more competent regarding time perception, accuracy in judging duration should be higher for the contralateral hand. The results of the present study indicated that there are no significant differences in performance between right-handed and left-handed participants, or between male and female participants, in the estimation of short intervals of time.

京都大学 / 新制・課程博士 / 博士(理学) / 甲第24076号 / 理博第4843号 / 新制||理||1693(附属図書館) / 京都大学大学院理学研究科生物科学専攻 / (主査)教授 中川 尚史, 准教授 中村 美知夫, 教授 中務 真人 / 学位規則第4条第1項該当 / Doctor of Science / Kyoto University / DGAM