Research was conducted in 2014 to evaluate the efficacy of harvest-aid systems and the performance of harvest aids applied at various timings in Mid-South soybean production. Evaluations included yield, desiccation, green stems and pods, and seed quality. Saflufenacil did not perform as well as the producer standard 14 DAT at the Starkville, MS location with desiccation levels of 78 and 98%, respectively. However, similar performance was observed 14 DAT at the Brooksville, MS location. When applied at R6.5, paraquat based treatments improved desiccation and reduced green stem 7 DAT compared to other treatments. No yield differences were observed between harvest aid treatments. However, yield differences were observed between the R6.0 and R6.5 timings. These data suggest saflufenacil is an effective harvest aid option, but may require up to 14 days for optimum desiccation. In addition, yield is not impacted by harvest aid product, but rather the timing of the application.