Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 5 uppsatser.

Thesis (M.S.)--University of Michigan, 1974. / Typescript (photocopy). Includes bibliographical references (leaves 65-69). Also issued in print.

Thesis (Ph. D.)--University of Virginia, 1997. / Spine title: Binding of peptides by class I molecules. Includes bibliographical references (164-204). Also available online through Digital Dissertations.

Thesis (M.S.)--University of Michigan, Ann Arbor, 1971. / Typescript (photocopy). Includes bibliographical references (leaves 48-51). Also issued in print.

Thesis (M.S.)--University of Michigan, 1974. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 65-69).

Thesis (M.S.)--University of Michigan, Ann Arbor, 1971. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 48-51).

Thesis (M.S.)--University of Wisconsin--Madison. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 37-40).

Thesis--University of Wisconsin--Madison. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 130-142).

Thesis--Wisconsin. / Includes bibliographical references (leaves 135-141).

Hydra is a simple freshwater solitary polyp used as a model system to study evolutionary aspects. The immune response of this organism has not been studied extensively and the immune response genes have not been identified and characterized. On the other hand, immune response has been investigated and genetic analysis has been initiated in other lower invertebrates. In the present study we took initiative to study the self/nonself recognition in hydra and its relation to the immune response. Moreover, performing phylogenetic analysis to look for annotated immune genes in hydra gave us a potential to analyze the expression of minor histocompatibility genes that have been shown to play a major role in grafting and transplantation in mammals. Here we obtained the cDNA library that shows expression of minor histocompatibility genes and confirmed that the annotated sequences in databases are actually present. In addition, grafting experiments suggested, although still preliminary, that homograft showed less rejection response than in heterograft. Involvement of possible minor histocompatibility gene orthologous in immune response was examined by qPCR.