The thesis is based upon research into the historical geography of the pastoral industry in the six major drainage basins in the North West of Western Australia, in an attempt to outline its early development, and to explain how the rangeland degeneration associated with the Big Drought of 1936-1946 was exacerbated by unrealistic official expectations and poor management, particularly of stations in the hands of absentee corporate owners. it discusses the failure of government agencies to appreciate the effects of overstocking in an environment characterised by climatic variability and fragile rangeland resources. It draws attention to the official reluctance to take action against the destructive activities of profit-seeking corporate owners in the period leading up to and including the Big Drought, and of speculative leaseholders in more recent times The thesis attempts to differentiate between the grassmen as leaseholders bent upon generating a sustainable income from the rangeland through conservative management, and the exploitative owners and their (often) incompetent managers. It identifies the specific characteristics of each of the basins in terms of the physical environment, the process of pastoral occupation and the resulting changing patterns of land use. It examines the changing nature of the habitat, economy and society of the Aboriginal people, from the days prior to European penetration up to the late 20th century It also considers the future prospects of the pastoral industry in each basin, with references to such issues as environmental impact, Aboriginal land rights and occupance, and the mining industry. As well as a comprehensive overview of the historical geography of each river basin, the thesis also includes a study of infrastructural elements and bf the activities of all groups of people involved in the development of the river basins.

This thesis deals with advertising of medicinal products for human use and its public law regulation contained especially in administrative law regulations. The thesis aims to bring information on the existing law in this area, explain particular legal institutes and propose potential amendments of the existing regulation in appropriate cases. The first chapter is devoted to definition of crucial terms of a medicinal product, advertising and public regulation, since their correct understanding is decisive for the following text. The second chapter concerns regulation of advertising, firstly in general and consequently concretely advertising of medicinal products for human use. The thesis is structured so that it concerns advertising focused on wide public separately from advertising focused on experts. The third chapter is devoted to responsibility, supervision, administrative proceedings and decisions in administrative judiciary, offences and sanctions in the area of regulation of advertising of medicinal products for human use. The fourth chapter analyzes main articles of the last proposal for amendment of the Act no. 40/1995 Coll., on Advertising Regulation, as amended, which was submitted to the legislative process in 2012, and contains de lege ferenda proposals. Annexes of the thesis contain...

International trade in pharmaceuticals Abstract The purpose of this thesis is to provide an analysis of the human pharmaceuticals international trade. This work examines the general questions of the diagonal relationships between states and private foreign pharmaceutical companies because there are a lot of many specific problems too. The author also focuses on questions concerning the contractual relationships of many stakeholders. There are many opportunities to beginning new directions in research innovative medicines and personalized medicine, but there are dangerous situations for the generic pharmaceutical market. Only a comprehensive knowledge and understanding of these relationships are efficient to develop new pathways to solving problems. The hypothesis of this dissertation text is the concept of efficiency good relationships to the stable distribution of the pharmaceutical products. There are many aspects of the relationships between stakeholders with possibility influencing of the final benefit from the business. Problems result from different interest, strength or weakness of stakeholders. In essence speaking, this thesis is divided into three parts. At first, with regard to our membership in the European Union, it was necessary to make the analysis some legislation of the European Union which...

Legal regulation of advertising of medicinal products in the Czech Republic Abstract This thesis deals with the advertising of medicinal products for human use and its development and legislation. The introductory part is set the objectives of this thesis and the reasons for choosing this topic. The first chapter is devoted to advertising, its legislation, the definition of advertising, history of advertising and this chapter also highlights the institution supervising advertising. The second chapter is to set the legal regulation of advertising in the Czech Republic. Regulation can be divided into the regulation of advertising public and private, together are in this dividing developed individual laws regarding advertising and is not omitted non-legal regulation of advertising. Ethical self-controller in this case especially the Rada pro reklamu and professional organizations. The third chapter is devoted to advertising of medicinal products for human use. This part is essential, because interpret basic definition related to medicinal products for human use. Further subdivision is dividing of medicinal product for human use. The basic consideration is whether product is successively authorised as a human medicinal product or not. In the case of an authorized as a human medicinal product dividing is...

Made available in DSpace on 2015-03-26T13:47:29Z (GMT). No. of bitstreams: 1 texto completo.pdf: 4069603 bytes, checksum: 86b254d515c67c4a265e4d713e51b915 (MD5) Previous issue date: 2007-01-29 / Conselho Nacional de Desenvolvimento Científico e Tecnológico / The drink water production to human use with adequate standards is very important to the health of consumers. At present, there are many researches in development to value the treatment of water in the world with support of World Health Organization and Health Treasury. On this context, the HACCP system is a important instrument to maintain the quality in water production. The studied supply system was the ETA/UFV, where were value in microbiologic and physical-chemical aspects of all treatment points to value the hazards. About the results, the ETA was according with the decree MS no 518/2004. Still, were value the associations of the protozoan (oo)cysts with others aspects as spores (aerobic e anaerobic), heterotrophic plate count, Clostridium perfringens, turbidity, color and solids. In this value of the plan was possible to suggest to introduction the points of the HACCP in the water treatment, valuing the action of al the treatment point (raw water, sedimentation, filters, disinfection and distribution) and the removal of all parameters. With this work, it was suggest as critical points the raw water, sedimentation, filters and disinfection. However, the HACCP is a system to reduce the risks to the health, valuing all the points and locate the faults, so, it is important to consider the estimation necessity of each production unit, in this case the water treatment, carrying own assessment to locate the hazards in the production to establish own limits and preventions. / A produção de água para consumo humano com padrões adequados de potabilidade é de suma importância para a saúde da população consumidora. Atualmente, diversas pesquisas têm sido realizadas sob a sugestão da Organização Mundial de Saúde e Ministério da Saúde, no intuito de avaliar as técnicas disponíveis no tratamento de água e propor novas tecnologias e, ou novos parâmetros de qualidade. Nesse contexto, o sistema APPCC apresenta-se como ferramenta viável no controle da produção de água. O sistema de abastecimento em estudo foi o da Universidade Federal de Viçosa (SAA-UFV) onde foram monitoradas todas as etapas de tratamento segundo parâmetros microbiológicos e físico-químicos a fim de identificar os perigos a partir de um diagrama de fluxo pré-elaborado. Segundo os resultados obtidos, o controle da qualidade da água produzida pela esteve sempre de acordo com os padrões estabelecidos pela Portaria MS no 518/2004. Foi verificado, ainda, correlações significativas entre (oo)cistos de protozoários e os parâmetros esporos (aeróbios e anaeróbios), contagem de bactérias heterotróficas, Clostridium perfringens, turbidez, cor e sólidos em suspensão, sendo necessários, entretanto, outros estudos para a adequada validação desses resultados. A avaliação inicial da produção de água na estação de tratamento de água da UFV (ETA-UFV) permitiu subsidiar a aplicação dos princípios do APPCC. Segundo as remoções dos parâmetros microbiológicos e físico-químicos verificadas em cada etapa, foram considerados pontos de atenção: captação, decantação, filtração, desinfecção e distribuição. Como pontos críticos de controle, foram considerados: captação, decantação, filtração e desinfecção. Há ainda de se considerar que, sendo o APPCC um plano que busca minimizar as chances de falhas no sistema de produção a partir de avaliações sistemáticas do processo, é necessário que cada unidade de produção, neste caso, as estações de tratamento de água, realize estudos preliminares para verificação de seus perigos, pontos críticos e medidas próprias de prevenção e, ou, controle.

L'influence européenne, notamment politique et juridique, la globalisation des échanges de médicaments de même que les conséquences de la globalisation - des crises sanitaires, économiques, financières - affectent les modalités d'organisation et d'exercice de la pharmacie d'officine française, italienne et anglaise. La convergence étant généralement présentée comme figurant au titre des conséquences possibles de l'européanisation et de la globalisation, les régimes français, italien et anglais de distribution de médicament à l'officine évoluent-ils vers une forme de « modèle juridique » commun, dépassant leur opposition historique ? En réalité, non seulement l'on assiste à l'émergence de modèles juridiques d'organisation et d'exercice de la pharmacie qui ne sont pas porteurs d'une unité susceptible de réduire de manière significative les différences entre les législations nationales, mais encore, cette unité n'est pas opportune. En effet, le maintien de spécificités nationales ainsi que l'adaptation des réglementations aux contextes nationaux apparaissent comme des éléments garants de l'efficacité des régimes nationaux de distribution officinale des médicaments. Pour autant, l'efficacité des réglementations ne se résume pas à la garantie des spécificités nationales de l'encadrement du secteur, comme l'illustrent les obstacles à la réparation des dommages imputables aux médicaments et à la protection du monopole pharmaceutique. Si certains apparaissent justement liés aux caractéristiques nationales, d'autres concernent de manière spécifique la lutte contre les ventes illégales de médicaments / European influence, especially political and legal, the globalisation of drug trade as well as the consequences of the globalisation of health, economic and financial crises impact the organisation and practice of French, Italian and English retail pharmacy. Convergence is generally presented as one of the possible consequences of europeanisation and globalisation. In effect, are the legal regimes of drug distribution in retail pharmacies in France, Italy and England evolving towards a common « legal model », beyond their historical opposition ? In reality, not only are we witnessing the emergence of organisational and operational retail pharmacy legal models that do not carry a unicity that would enable significantly reducing differences between national legislations, but this unicity would not be timely. Indeed, the preservation of national specificities, as well as the adaptation of regulations to national contexts appear as key guarantors of the efficacy of retail pharmacy drug distribution national legal regimes. However, the efficacy of regulations cannot be summarised to guaranteeing the sector’s national specificities, as illustrated by the obstacles to compensation for damages attributable to medicines and to the protection of the pharmaceutical monopoly. While some of these obstacles appear precisely linked to national characteristics, others relate specifically to the war against illegal drug sales