Multiple customer needs and rapid technological change are what MNCs are confronted with, thus, they rely on subsidiaries responding to local market needs. The ability of subsidiaries to integrate resources to respond to market opportunities determines its competitiveness, and contributes to whole corporate. The purpose of this dissertation is to construct an integrative framework toward generating subsidiary initiatives and competitiveness. Structural equation modeling was employed to verify the conceptual framework. Based on the results of SEM, entrepreneurial leadership of top management teams enhances the talent on the process of human-capital leveraging to facilitate them to be creative and agile; further, promote collective learning among members. Additionally, with the support of top management teams, learning culture of subsidiaries can be strengthened. Support of top management team, human-capital leveraging and learning culture, improve the absorptive capacity, further, they promote subsidiary initiatives and competitiveness.