This thesis describes the study of the hydrodynamic boundary condition at the solid-liquid interface using the colloidal probe Atomic Force Microscope. Quantitative comparison between measured lubrication forces and theoretical lubrication forces show that the measured forces agree with theory when the no slip boundary condition is employed. We measure an effective slip length of 0 ± 2 nm at shear rates up to 250,000 sec-1. Our results are consistent with the Taylor lubrication equation without the need to invoke a slip length fitting parameter. Our results are also consistent with molecular dynamic simulations that predict no slip at the shear rates that are currently experimentally accessible.

This thesis describes the study of the hydrodynamic boundary condition at the solid-liquid interface using the colloidal probe Atomic Force Microscope. Quantitative comparison between measured lubrication forces and theoretical lubrication forces show that the measured forces agree with theory when the no slip boundary condition is employed. We measure an effective slip length of 0 ± 2 nm at shear rates up to 250,000 sec-1. Our results are consistent with the Taylor lubrication equation without the need to invoke a slip length fitting parameter. Our results are also consistent with molecular dynamic simulations that predict no slip at the shear rates that are currently experimentally accessible.