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Improving tolerance to hypoxia in the eastern oyster, Crassostrea virginicaFord, Courtney B., Wallace, Richard K. January 2005 (has links) (PDF)
Thesis(M.S.)--Auburn University, 2005. / Abstract. Vita. Includes bibliographic references.
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Behavior of juvenile estuary-dependent fish in relation to the spatial and temporal dynamics of diel-cycling hypoxia in an estuarine tributaryBrady, Damian C. January 2008 (has links)
Thesis (Ph.D.)--University of Delaware, 2008. / Principal faculty advisor: Timothy E. Targett, College of Marine and Earth Studies. Includes bibliographical references.
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Dynamics of dissolved oxygen and benthic release of nutrients in the bottom water layer in shallow versus deep areas in Hong Kong waters /Chong, Kit Yee. January 2010 (has links)
Ph.D. in Marine Environmental Science. Includes bibliographical references (145-158).
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Hypoxia and Macoma balthica : ecological effects on a key infaunal benthic species /Long, William Christopher. January 2007 (has links) (PDF)
Thesis (Ph. D.)--College of William and Mary. / Vita. Includes bibliographical references.
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Interferon-gamma/Hypoxia Primed Mesenchymal Stem Cells for an Improved Immunosuppressive Cell TherapyWobma, Holly Michelle January 2018 (has links)
Mesenchymal stem cells (MSCs) are promising candidates for treating diverse inflammatory disorders due to their capacity to be immunosuppressive. This phenotype is not present at baseline but develops in response to instructive cues. To date, clinical trials use cells grown in basic culture conditions, anticipating the cells will acquire a useful phenotype in response to in vivo cues. This strategy has failed to produce any FDA approved therapies, based on inconsistent efficacy. This thesis explores whether priming MSCs prior to administration can lead to a more uniformly therapeutic phenotype, and it details the design of an optimal in vitro priming regimen. Because interferon gamma (IFN-γ) is known to induce an anti-inflammatory state in MSCs, hypoxia can confer survival benefits, and both cues coexist in known situations of immune tolerance, we hypothesized dual IFN-γ/hypoxia priming would yield a superior immunosuppressive MSC therapy. We show that priming MSCs with hypoxia or IFN-γ alone improves their ability to inhibit T-cells in vitro, but combining these cues results in additive improvements. We next characterize the proteomic and metabolomic changes MSCs undergo when exposed to single or dual IFN-γ/hypoxia priming. While IFN-γ induces MSCs to suppress inflammation and fibrosis, hypoxia leads to cell adaptations to low oxygen, including upregulation of proteins involved in anaerobic metabolism, autophagy, angiogenesis, and cell migration. Dual priming results in additive effects, with many instances of synergy. Finally, we show initial evidence that dual primed MSCs are better able to inhibit disease progression in a mouse model of acute graft-vs-host disease (GvHD).
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Geochemistry of manganese and iron across both stable and dynamic natural oxic-anoxic transition zonesTrouwborst, Robert Elisa. January 2006 (has links)
Thesis (Ph.D.)--University of Delaware, 2006. / Principal faculty advisor: George W. Luther, III., College of Marine and Earth Studies. Includes bibliographical references.
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Effect hypoxia has on feeding and egg production rates of Acartia tonsa Dana 1849 (Copepoda: Calanoida)Sedlacek, Chris. Marcus, Nancy. January 2003 (has links)
Thesis (M.S.)--Florida State University, 2003. / Advisor: Dr. Nancy Marcus, Florida State University, Dept. of Oceanography. Title and description from dissertation home page (viewed Mar. 2, 2004). Includes bibliographical references.
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Examining the prey resource value of diel-cycling hypoxia impacted benthic habitat for juvenile weakfish (Cynoscion regalis) and summer flounder (Paralichthys dentatus) in an estuarine tributaryTuzzolino, Danielle. January 2008 (has links)
Thesis (M.S.)--University of Delaware, 2008. / Principal faculty advisor: Timothy E. Targett, College of Marine & Earth Studies. Includes bibliographical references.
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Hypoxic gene regulation and high-throughput genetic mapping. /Baird, Nathan Alder, January 2008 (has links)
Thesis (Ph. D.)--University of Oregon, 2008. / Typescript. Includes vita and abstract. Includes bibliographical references (leaves 45-52). Also available online in ProQuest, free to University of Oregon users.
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An examination of the neuroprotective strategies used by the epaulette shark in response to hypoxia /Wise, Graham. January 2003 (has links) (PDF)
Thesis (Ph.D.) - University of Queensland, 2005. / Includes bibliography.
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