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A matched case-control study of the epidemiology of insulin-dependent diabetes mellitus in childhoodMarshall, Anna Louise January 2000 (has links)
No description available.
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Regenerating gene (reg) expression : studies in the BB rat and manBanister, Susan H. January 1992 (has links)
No description available.
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Cellular and molecular pathology of disease progression in a model of insulin dependent diabetes mellitusLally, F. J. January 2000 (has links)
No description available.
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Calcium homeostasis and blood pressure regulation in normal and insulin-dependent diabetic pregnancyDunlop, Diana Clare January 1999 (has links)
No description available.
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MATERNAL DEPRESSIVE SYMPTOMS AND HEALTH OUTCOMES IN YOUTHS WITH TYPE 1 DIABETES: A MEDIATIONAL MODELMorgan, Struemph Kari 08 December 2010 (has links)
Objectives: The rate and impact of depressive symptoms were examined with two models based on known effects of depression on variables related to diabetes management, parental involvement and diabetes conflict. The proposed models will measure potential effects high maternal depressive symptoms may have on parental monitoring and involvement and diabetes specific conflict and how these variables may in turn relate to poor regimen adherence. Methods: Participants included 225 mothers and young adolescents (aged 11-14) with T1D. Diabetes self-care behaviors were measured with the 24 Hour Recall Interview, parental involvement and monitoring were measured with the Parent Management of Diabetes Scale, and diabetes specific conflict was measured with the Diabetes Family Conflict Scale. Results: A significant portion of mothers (21%) reported clinically elevated levels of depressive symptoms. These high levels of depressive symptoms were related to low levels of parental involvement with diabetes care (r = -.19, p < .01). Depressive symptoms were indirectly related to lower frequency of blood glucose monitoring (C.95 = -.03, -.002), insulin use (C.95 = -.01, -.0007), and meals (C.95 = -.02, -.002) through low levels of parental involvement. Higher levels of depressive symptoms were also related to higher levels of diabetes specific conflict (r = .16, p < .01), however, this relationship did not have a significant indirect effect on frequency of self-care behaviors. Conclusions: A significant portion of mothers in the current sample reported symptoms of depression above the clinical cutoff. Mothers that reported higher levels of depressive symptoms also reported lower levels of parental involvement in management of disease-care behaviors. Low levels of parental involvement mediated a significant relation between depressive symptoms and less frequent disease-care behaviors. Diabetes conflict did not mediate a relation between depressive symptoms and disease-care behaviors. These findings suggest that the reported high levels of maternal depressive symptoms among mothers of children with T1D may interfere with good diabetes management through low parental involvement. Individual treatment for depressive symptoms and interventions targeted at increasing parental involvement without increasing diabetes conflict could help improve regimen adherence.
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Parental Memory Predictors of Children's Daily Diabetes Management and Metabolic ControlKent, Sheryl J. 01 January 2005 (has links)
This study examined, for the first time, specific links between parents' memory and children's diabetes behaviors and metabolic control. Data revealed that parental memory and responsibility predicted children's percentage of calories from fat and carbohydrates, and metabolic control, accounting for 7.3% of the variance in calories from fat and 18.5% of the variance in metabolic control for the total sample. These effects were stronger when limited to dietary behaviors of younger youth; parental memory accounted for 30.3% and 33.6% of the variance in percentage of calories from fat and carbohydrates, respectively, for younger children. Level of parent responsibility, with memory, moderated younger children's percentage of calories from fat and carbohydrates, and children's metabolic control. Parents with higher memory scores and more responsibility had disease indictors that were closer to ADA recommendations. Results suggest intervention to enhance parent memory may improve diabetes care and health status for youths with IDDM.
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Informovanost veřejnosti o diabetu mellitu / Public awereness about diabetes mellitusKNÍŽOVÁ, Kateřina January 2009 (has links)
Diabetes mellitus belongs to diseases frequently occurring in childhood and adulthood. Insufficient knowledge of this disease and an unsatisfactory compensation for diabetes leads to development of late complications that have a negative impact on one's, as well as the family's, life and create an economic problem for society as a whole. The thesis focuses on the main characteristics of the disease, symptoms, diagnosis and treatment. Complications of the disease, including advice for patients themselves and their prevention are described in more detail. Social aspects (work inclusion of a diabetic, invalidity and reduced work capacity, driving of motor vehicles) are also emphasised. The research part containing 18 questions aims to find out to what extent the Czech public is informed about the problematic areas of this disease. It also assesses the feasibility of obtaining information from individuals of different ages and places of residence (city vs. village) regarding diabetes. These hypotheses were stated within the scope of the research: 1. Individuals older than 50 years of age are better informed about diabetes than individuals of a younger age. 1. Individuals living in a city have a better access to information concerning diabetes than individuals living in a village. The data was obtained from questionnaire research, in which respondents older than 18 years of age participated. The data collection took place in Bechyně Spa Ltd. 58 % of the resultant questionnaires were completed by women and 42 % by men.
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The Effects Of Insulin-dependent Diabetes Mellitus On Cognitive Functioning, Learning Difficulties, And Behavioral Problems In ChildrenAkay, Sinem 01 January 2010 (has links) (PDF)
The aim of the present study was to investigate the influence of insulin-dependent
diabetes mellitus (IDDM) on the cognitive functioning, learning difficulties, and
behavioral problems in children between the ages of 7 and 12. The sample was
composed of elementary school children living in Ankara, Turkey. Data was
collected by administering demographic information form, Children&rsquo / s Depression
Inventory (CDI), Strength and Difficulties Questionnaire (SDQ), Wechsler
Intelligence Scale for Children&ndash / Revised (WISC-R), and Specific Learning Disability
Scale. One-way ANOVAs were employed to examine the differences among the
levels of parental education, income, school achievement, and child&rsquo / s adherence to
IDDM in terms of WISC-R scores, learning difficulty related variables, behavioral
problems, and depression. Results revealed that children with low adherence to
IDDM were more likely to experience behavioral problems and depression. T-tests
were conducted to examine the mean differences between IDDM and control groups
in terms of WISC-R scores, and the variables related to learning difficulties,
behavioral problems, and depression. As compared to control group, children with
IDDM had lower WISC-R information, similarities, arithmetic, and total scores. Also, children with IDDM had lower achievement in several arithmetic, reading, and writing tasks. Furthermore, hierarchical multiple regression analyses were conducted to test the effect of IDDM adherence, age of onset, and illness duration on cognitive functioning, learning, and behaviors. The results did not reveal any significant effect of IDDM related variables on children&rsquo / s cognitive functioning, learning, or behaviors. Findings were discussed with reference to the relevant literature. Implications of the study were discussed and future research topics were suggested.
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Sexual function in women with neurological disordersHulter, Birgitta January 1999 (has links)
<p>The purpose of this investigation was to study sexual function in women with neurological disorders at fairly distinct and separate locations. The dissertation comprises descriptive, retrospective, quantitative studies on sexual functioning in women with hypothalamo-pituitary disorders (HPD) (<i>n</i>:48), multiple sclerosis (MS)(<i>n</i>:47), and insulin-dependent diabetes mellitus (IDDM) (<i>n</i>:42). The results werecompared with those in an age-matched control group (C) (<i>n</i>:42), and as reported by representative Swedish women (<i>n</i>:742) in the Swedish sex survey SiS). The studies were based on comprehensive interviews, neurological examinations, incl. Vibration Perception Thresholds (IDDM), concentrations of prolactin and testosterone in serum (HPD), and a checklist on life satisfaction (IDDM, C, and SiS).</p><p>Sexual dysfunction was prevalent in almost all women with HPD and MS, and in 40% of the IDDM group. The problem of insufficient vaginal lubrication was more common in those with neurological disorders than among women in the SiS group. Sexual problems caused by reduced libido and orgasmic difficulties were more commonin the HPD and MS groups than in the SiS group. In the HPD group, women with intrasellar adenomas had better sexual function than women having expansively growing pituitary adenomas with both intra- and suprasellar extension. Normal serum testosterone values correlated to masturbation activity. Amenorrhea and older age werecorrelated with sexual problems in all groups. In the MS group, symptoms of a weak pelvic floor and of bladder and bowel dysfunction were correlated with reduced lubrication and orgasmic ability. In the IDDM group, signs of autonomic neuropathy were correlated with sexual dysfunction. Concerning life satisfaction generally,proportionately fewer women with IDDM were satisfied or very satisfied, though differing significantly from the other two groups in only two domains of life: contacts with friends, and physical health.</p>
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Sexual function in women with neurological disordersHulter, Birgitta January 1999 (has links)
The purpose of this investigation was to study sexual function in women with neurological disorders at fairly distinct and separate locations. The dissertation comprises descriptive, retrospective, quantitative studies on sexual functioning in women with hypothalamo-pituitary disorders (HPD) (n:48), multiple sclerosis (MS)(n:47), and insulin-dependent diabetes mellitus (IDDM) (n:42). The results werecompared with those in an age-matched control group (C) (n:42), and as reported by representative Swedish women (n:742) in the Swedish sex survey SiS). The studies were based on comprehensive interviews, neurological examinations, incl. Vibration Perception Thresholds (IDDM), concentrations of prolactin and testosterone in serum (HPD), and a checklist on life satisfaction (IDDM, C, and SiS). Sexual dysfunction was prevalent in almost all women with HPD and MS, and in 40% of the IDDM group. The problem of insufficient vaginal lubrication was more common in those with neurological disorders than among women in the SiS group. Sexual problems caused by reduced libido and orgasmic difficulties were more commonin the HPD and MS groups than in the SiS group. In the HPD group, women with intrasellar adenomas had better sexual function than women having expansively growing pituitary adenomas with both intra- and suprasellar extension. Normal serum testosterone values correlated to masturbation activity. Amenorrhea and older age werecorrelated with sexual problems in all groups. In the MS group, symptoms of a weak pelvic floor and of bladder and bowel dysfunction were correlated with reduced lubrication and orgasmic ability. In the IDDM group, signs of autonomic neuropathy were correlated with sexual dysfunction. Concerning life satisfaction generally,proportionately fewer women with IDDM were satisfied or very satisfied, though differing significantly from the other two groups in only two domains of life: contacts with friends, and physical health.
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