No description available.

Thesis (M.P.H.M.)--Mahidol University, 1999.

Thesis (M.A.)--Boston University / Since the discovery of VI antigen by Felix and Pitt in 1934 (The Lancet, 2:186, 1934), investigators have attempted to isolate, purify and characterize this antigen. Antisera against purified VI antigens would prove a valuable tool for studying the effects of purification on the antigenic molecule. Purified Vi antigen, however, has proven to be a hapten in rabbits with one exception. Landy and Webster's Vi preparation was immunogenic for rabbits as well as for mice (J. Immunol., 69:143, 1952) but the preparations of Ashida (Japan. J. Exper. Med., 20:181, 1949), and of Baker, et al (J. Immunol., 83:687, 1959) were non-immunogenic although Baker's preparation immunized mice and man. Landy and Webster, however, observed that more of their preparation than of whole organisms was necessary to immunize rabbits to an equal degree [TRUNCATED]

Thesis (M.A.)--Boston University / PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you. / Outer membrane proteins from unencapsulated(nontypable) Haemophilus influenza were prepared by incubation with EDTA and shearing followed by molecular sieve chromatography in a lipooligosaccharide (LOS) disaggregating deoxycholate buffer. Outer membranes proteins collected were determined to be free of LOS by polyacrylamide gel electrophoresis and then covalently attached to cyanogen bromide activated Sepharose. Antibodies to outer membrane proteins were then isolated by affinity chromatography and characterized by enzyme-linked immunosorbant assay. These antibodies will prove useful for passive immunization experiments to establish the role of outer membrane proteins in host protection from infection with nontypable Haemophilus influenza. / 2031-01-01

Background. Neonatal tetanus occurred in a 7-day-old infant born to Mexican immigrant parents in Tennessee in February, 1995. This was the first patient with neonatal tetanus reported in the United States since 1989. Methods. We interviewed the infant's mother and physicians and reviewed the medical record. We conducted a telephone survey of 103 (17%) of the 609 licensed obstetrician/gynecologists practicing in Tennessee to assess vaccination history-taking practices during prenatal care. Results. The mother was a 30-year-old gravida 4 para 3 woman who grew up in rural Mexico. After moving to the United States in 1987, she had delivered two children before this delivery. The hospital-based delivery and nursery stay in February, 1995, were uncomplicated. On the sixth day of life the infant became irritable and developed muscle stiffness. The next day he was examined by a pediatrician who diagnosed neonatal tetanus. The infant recovered fully after a 2-month hospitalization. The survey of obstetrical practices revealed that 61 (59%) of 103 respondents asked about the patient's vaccination status during prenatal care. However, of all respondents, only 14 (14%) confirmed that they specifically asked about prior tetanus vaccinations. Tetanus toxoid was available in 47% of offices on the day of the survey. Conclusions. Neonatal tetanus can still occur in the United States. This infant's immigrant mother had multiple missed opportunities to be vaccinated against tetanus during her three pregnancies in this country. Health care providers should ask patients about their vaccination status, particularly those patients who are foreign-born or who grew up outside the United States.

Thesis (M.S.)--University of Michigan 1979.

Thesis (M.S.)--University of Michigan, 1997. / Includes bibliographical references.

Thesis (doctoral)--Lund University, 1994. / Added t.p. with thesis statement inserted.

Thesis (M.S.)--University of Michigan, 1982.

Thesis (M.S.)--University of Michigan 1979.