The use of antibiotics as prophylaxis against postsurgical infection has been propagated. However, in the field of oral implant dentistry, the use of systemic antibiotics remains a controversial issue, with various antibiotic regimens being advocated. The aims of this multi-center randomized clinical trial were to determine the effect of various systemic antibiotic prophylaxis regimens on patient-centered outcomes and perceptions, postsurgical complications in patients undergoing standard oral implant therapy. In this preliminary study, 107 medically healthy adults who were consecutively admitted to 5 study centers for standard oral implant therapy were randomly assigned to one of the 4 groups (3 test and 1 control groups). Pre-operative antibiotics of 2 g amoxicillin 1 hour prior to standard implant placement were prescribed to test group 1 (positive control), post-operative antibiotics of 2g amoxicillin following implant placement for test group 2, and pre-operative antibiotics of 2g amoxicillin 1 hour prior to standard implant placement and 500mg three times daily on days 2 through 3 after standard implant placement for test group 3. The control group was given a placebo tablet of 2g 1 hour prior to standard implant placement without any antibiotics. Subjects were examined clinically by blinded examiners at 1 week, 2 weeks, 4 weeks and 8 weeks from implant installation for post-operative complications. In addition, Visual Analogue Scales (VAS) on pain, swelling, bruising and bleeding were obtained from the patients from Day 1 through Day 7 and 14. From the results of this preliminary study, in standard single implant placement with non-submerged healing, the postoperative complications (Flap closure, Swelling, Pain, Suppuration and Implant stability) and patient-centered outcomes (VAS of bleeding, pain, swelling and bruising) will neither be affected by using antibiotics prophylaxis in different regimens nor not using antibiotics prophylaxis. It should be reiterated that dental practitioners should be cautious when using antibiotics as a prevention of postoperative infection in dental implant therapy. The indiscriminate use of antibiotics will eventually lead to more serious consequences including allergy and the development of resistance strains. / published_or_final_version / Dental Surgery / Master / Master of Dental Surgery

Bone morphogenetic protein-2 (BMP-2) plays a critical role in bone formation. The aim of this study was to compare the activity of the mammalian cell BMP-2 to the E-coli cell BMP-2. In vitro, the potency of mammalian and E-coli BMP-2 was compared by adding BMP-2 to C2C12 cells and measuring the level of alkaline phosphatase activity. In vivo, the activity was evaluated by placing the bioimplants in the thigh muscle of mice, and measuring the amount of bone induced. The in vitro assay clearly showed that mammalian BMP was significantly more potent than E-coli BMP. In vivo, on the calcium phosphate carrier, mammalian BMP produced more bone than E-coli BMP, but E-coli BMP produced higher density tissue than mammalian BMP. On both mammalian and E-coli BMP, the calcium phosphate carrier had a significant effect on the density but not the quantity of bone produced versus the absorbable collagen sponge carrier.

No description available.

Bone morphogenetic protein-2 (BMP-2) plays a critical role in bone formation. The aim of this study was to compare the activity of the mammalian cell BMP-2 to the E-coli cell BMP-2. In vitro, the potency of mammalian and E-coli BMP-2 was compared by adding BMP-2 to C2C12 cells and measuring the level of alkaline phosphatase activity. In vivo, the activity was evaluated by placing the bioimplants in the thigh muscle of mice, and measuring the amount of bone induced. The in vitro assay clearly showed that mammalian BMP was significantly more potent than E-coli BMP. In vivo, on the calcium phosphate carrier, mammalian BMP produced more bone than E-coli BMP, but E-coli BMP produced higher density tissue than mammalian BMP. On both mammalian and E-coli BMP, the calcium phosphate carrier had a significant effect on the density but not the quantity of bone produced versus the absorbable collagen sponge carrier.

No description available.

Management systems that enhance carcass yield can increase the efficiency and competitiveness of beef producers, but meat quality should not be negatively affected. Continental or British crossbred steers were finished to either 12 to 13 or 18 to 20 months of age and were either untreated or treated with hormonal implants, ractopamine hydrochloride, or both. Slaughtering steers at 18 to 20 month of age, using British-Continental crossbreeding, and implanting steers reduced meat tenderness but meat yield was greater than that of 12 to 13 month old steers, British-British crossbred steers, and non-implanted steers. Decreased meat tenderness was associated with increased myofibre diameter and reduced collagen solubility. Slaughtering at 18 to 20 months of age, hormonal implants, and ractopamine hydrochloride reduced meat water-holding capacity. Muscle weight appeared to be the best indicator of shear force and it may cumulatively represent complex changes related to age and growth that occur in muscle. / Animal Science

Thesis (M.D.S.)--University of Adelaide, 1987. / Typescript. Includes bibliographical references (leaves 131-167).

Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2007. / Härtill 4 uppsatser.

Thesis (MScIng)--University of Stellenbosch, 2007. / Bibliography. Also available via the Internet.

Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references. Also available in print.