Taiwan is a country with limited land resources and a dense population. Regarding national land, it should be effectively and comprehensively utilized, developed and maintained so that industries can have appropriately allocation and development under regional planning in the hope to improve national welfare. However, Taiyen Biotech Co., Ltd. (Taiwan Salt Industrial Corporation) has terminated solar salt work completely since 2002 and returned 5,243 hectares of land to National Property Administration. The re-development and use of land has remained under review consideration. The solar salt economic activities that once supported tens of thousand of people have ground to a halt due to the termination of solar salt work, leaving salt fields unattended. And salt villages have become desolate. It is a shame to see the unattended salt fields soak in sea water and turn into marshes. The author tries to study from the viewpoint of National Comprehensive Development Plan and its relation with industrial development and present three industrial cluster-based economy science park development projects. They can provide choices for the government to make effective management guidelines in National Comprehensive Development Plan. By re-invigorating regional industrial economy in the country, we may expect to build new prosperous science and technology townships. Keywords: development, National Comprehensive Development Plan, industrial cluster-based economy, project, regional economy.