The purpose of this study was to examine social workers’ perspectives on the risk factors that are associated with cases of removal of infants. A quantitative survey design was utilized, using self-administered questionnaires that were distributed electronically to social workers located in San Bernardino County. The sample consisted of 94 participants, and the majority of the participants were White, non-Hispanic females. The study found that social workers identified substance abuse, the lack of infant’s physical safety in the home along with the age of the infant, and the lack of parents’ readiness to take part of the safety plan as highest risk factors for the removal of infants. Lastly, a surprising finding in this study was that a child’s ethnicity was indicated as a risk factor that increases the possibility of infant removal. It is recommended that social workers continue to receive trainings and other educational opportunities to enhance the social workers’ knowledge, values, and practice skills, to ensure the safety and well-being of all children.