Over the past several years, experiments in adaptive optics involving multiple natural and laser guide stars have been carried out at the 1.55 m Kuiper telescope and the 6.5 m MMT telescope. The astronomical imaging improvement anticipated from both ground-layer and tomographic adaptive optics has been calculated. Ground-layer adaptive optics will reduce the effects of atmospheric seeing, increasing the resolution and sensitivity of astronomical observations over wide fields. Tomographic adaptive optics will provide diffraction-limited imaging along a single line of sight, increasing the amount of sky coverage available to adaptive optics correction.A new facility class wavefront sensor has been deployed at the MMT which will support closed-loop adaptive optics correction using a constellation of five Rayleigh laser guide stars and the deformable F/15 secondary mirror. The adaptive optics control loop was closed for the first time around the focus signal from all five laser signals in July of 2007, demonstrating that the system is working properly. It is anticipated that the full high-order ground-layer adaptive optics loop, controlled by the laser signals in conjunction with a tip/tilt natural guide star, will be closed in September 2007, with the imaging performance delivered by the system optimized and evaluated.The work here is intended to be both its own productive scientific endeavor for the MMT, but also as a proof of concept for the advanced adaptive optics systems designed to support observing at the Large Binocular Telescope and future extremely large telescopes such as the Giant Magellan Telescope.