The increased moisture of the building materials causes the change of its mechanical and physical characteristic. In particular the high amount of loose water in construction shorten the lifetime of the building, is harmful to human beings due to biotic factors and increase the economic expenses of usage of the building. Apart from the costs of rehabilitation the loose water deteriorates the thermal insulative ability (thermal conductivity coefficient ) of perimeter masonry as well. The moisture gets into masonry not only through its deffects but also due to many different reasons. In order to improve the utility value of the buildings we have to deal with the rehabilitation of damp masonry with view to all possible causes. Only the properly working damp proofing ensures the protection against the water leaking from the subfoundation of the building. One of the direct techniques which have undergone rapid progress in last few years is the injection procedure. With use of experimental methods in my dissertation I deal with evaluation of two injection compounds used in Czech Republic and with its impact on the characteristics of the mortar. With the modern hollow bricks (system THERM) it is possible to create horizontal infusion into the lateral mortar grooves in future.

Type 1 diabetes affects a person’s life on many levels in terms of quality of life, health, and socioeconomic costs both for the patients but also their families. As of now there is no therapy that targets the underlying mechanism of the disease. Intralymphatic administration of Diamyd® is being evaluated in a phase IIb clinical trial, DIAGNODE-2. The aim was to examine if the intralymphatic administration is feasible for both patients and medical professionals, and to identify any aspects of the procedure that can be improved. This feasibility study is based on interviews and answers received from questionnaires. The medical professionals that were selected were radiologists and study nurses that are involved in the DIAGNODE-2 trial. The radiologists were the prime focus and were thus interviewed through face-to-face/skype or phone and answered a questionnaire. Study nurses, having more contact with the patient, answered a survey in order to gain additional insights into the patient perspective.   The results show that the radiologists has a positive view towards the administration procedure, which was described as easy and safe. According to the study nurses the patients accept the procedure and they agreed that the patients understand the injection procedure once they received the information. In terms of the emotional state of the patients they were a bit nervous, but they became calmer after receiving the first injection. Based on the above-mentioned findings the intralymphatic injection procedure is described as feasible and has the potential to become a part of the standard clinical routine.