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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Ion movements in the nervous system of the cockroach, Periplaneta americana L. influenced by toxaphene in vitro

Whitson, Roy Stanley January 1978 (has links)
No description available.
2

Evidence of hysteresis in the neuromuscular system of 3rd instar Sarcophaga bullata /

Paterson, Bethany A. January 2008 (has links) (PDF)
Undergraduate honors paper--Mount Holyoke College, 2008. Dept of Biological Sciences. / Includes bibliographical references (leaves 42-45).
3

Imaging calcium dynamics during motor pattern generation and sensory processing in insect nervous systems

Bayley, Timothy George January 2016 (has links)
No description available.
4

Myc-based cell competition requires regulation of ecdysteroid levels by the peptide hormone Dilp8

Bellah, Jeffrey Lawrence January 2024 (has links)
Though all the cells of the same cell type in a tissue of a multicellular organism may appear interchangeable, this is not always the case. Throughout an organism’s lifespan, they will encounter many insults that lead to damage or mutation of cells, introducing heterogeneity into otherwise near homogeneous tissues. In the case deleterious heterogeneities, such as cells with decreased ability to grow, it benefits the organism to have fitness sensing mechanisms that can detect these cells and eliminate them. Cell competition was first identified as a mechanism that eliminates slower growing cells possessing ribosomal protein mutations in mosaic tissues with normally growing cells. Since its discovery, cell competition has been found to be induced by numerous genetic differences, including instances where the wild-type cells are eliminated by faster growing cells overexpressing the growth factor Myc, termed Myc super-competition. Though cell competition is primary viewed as a local cell-to-cell signaling event that determines fitness and eliminates less-fit cells, in this dissertation I identify a novel function of the steroid hormone ecdysone as a systemic, restrictive regulator of Myc super-competition in Drosophila. I find that Dilp8-Lgr3 signaling in the central nervous system represses ecdysone biosynthesis to systemically maintain a low-ecdysone, permissible environment for Myc super-competition. In further work that has begun probing how the level of systemic ecdysone prevents neighboring cell populations from undergoing Myc super-competition, I have found that the level of Myc in cells interacts with ecdysone through a variety of mechanisms, including being able to upregulate Dilp8 and downregulate the ecdysone receptor complex. This work lays the foundation for further work to investigate the mechanism by which ecdysone regulates Myc super-competition.

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