This thesis describes the prevalence, determinants and dynamics of intergenerational sexual relationships in urban Botswana. The study was conducted in three stages, the survey, in-depth interviews and radio talk-back. The survey was conducted with schoolgirls in all four public senior secondary schools in Gaborone, Botswana. The survey was completed first before proceeding to the other two stages. However, the last two stages were done concurrently. A quantitative survey was conducted with 600 schoolgirls (18-22-year-olds) in order to establish their sexual practices, find out the prevalence of intergenerational sexual relationships among them and find out their perceptions regarding intergenerational sexual relationships. More than three-quarters of the participants had boyfriends in their age group and about one-quarter of those who were approached by older men had older boyfriends. The results revealed the practice of multiple sexual partners both in intragenerational and intergenerational sexual relationships. The issue of multiple sexual partners has been identified to be one of the factors that fuel STI/HIV infections. Girls who were in intergenerational sexual relationships have positive perceptions and attitudes towards them. However, the majority of the girls did not perceive such relationships as good. They associated them with the danger of engaging in unprotected sex and thus a greater risk of contracting STI/HIV.