The multi-speed internal gear hub of a bicycle is a well-closed gear shifting system that works perfectly under any challenging riding environment, and is developed specifically to improve fragile chain-drive derailleur using planetary gear trains. In recent years, bicycle internal hub gears have been developed toward multi-speed transmission, and in the development process of internal gear hubs, the structure of speed changing mechanism has changed from a single planetary gear train to multiple planetary gear trains, and is becoming more complex. The primary purpose of this Study aims to establish a systemized and efficient design process, and develop an effective theory and method for designing multiple-speed internal gear hubs with the design concept and common features of multiple-speed internal gear hub products developed in recent years, to favor the innovation and development of internal gear hubs. First, existing multiple speed internal hub products are analyzed and summarized for their basic features, limitations, and demands as the reference for the design of multiple speed internal gear hubs, and a catalog of usable planetary structures is systematically established with the coupling and connection of basic high and low ratio speed changing modules. Secondly, usable planetary structures that offer best performance of geometric progression speed ratio distribution of gear hub are matched with gear positions, and a table of gear sequence is confirmed; third, based on the maximum external diameter required by design, tooth numbers for every gear in a hub are defined according to the relationship between tooth number and speed ratio, as well as the gear sequences; and finally, the systematic design process above is applied to the development of an easy-to-use computer aided design software with the lowest possible number of variables using Visual Basic 6.0 for designers, in order to favor the innovation and development of internal gear hubs.